916225-92-8Relevant articles and documents
Total synthesis of (±)-morphine
Uchida, Kenji,Yokoshima, Satoshi,Kan, Toshiyuki,Fukuyama, Tohru
, p. 1219 - 1234 (2009)
The morphinan skeleton was effectively synthesized by an intramolecular Mannich-type reaction. Further transformation led to the total synthesis of morphine.
Synthesis of santiagonamine
Markey, Michael D.,Ying, Fu,Kelly, T. Ross
, p. 3255 - 3257 (2008/02/11)
The first total synthesis of santiagonamine (1) is achieved in 12 steps from isovanillin. A palladium-catalyzed Ullmann cross-coupling reaction and a photocyclization are the key steps in the synthesis.