151726-41-9

Upstream product

• 5779-98-6 O-methoxymethylisovanillin 
• 149-73-5 trimethyl orthoformate 
• 212914-85-7 isovanilin 
• 621-59-0 isovanillin 
• 59276-36-7 isovanilline dimethyl acetal 
• 107-30-2 chloromethyl methyl ether 

Downstream Products

• 916225-90-6 2-iodo-4-methoxy-3-(methoxymethoxy)-1-(dimethoxymethyl)benzene 
• 125-29-1 Hydrocodone 
• 151726-44-2 (1R,8aR)-1-(3-Benzyloxy-2-iodo-4-methoxy-benzyl)-2-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-1,2,3,4,6,7,8,8a-octahydro-isoquinoline 
• 151726-45-3 C₃₉H₃₉NO₂ 
• 151726-51-1 2-(3-Benzyloxy-2-iodo-4-methoxy-phenyl)-oxirane 
• 151726-43-1 (3-Benzyloxy-2-iodo-4-methoxy-phenyl)-acetaldehyde 
• 151726-42-0 3-(benzyloxy)-2-iodo-4-methoxybenzaldehyde 
• 138490-94-5 2-iodoisovanillin 
• 811819-66-6 3-benzyloxy-N-[2-(1,4-dioxaspiro[4,5]dec-7-en-8-yl)ethyl]-2-iodo-4-methoxy-N-methyl-benzamide 
• 811819-69-9 9-benzyloxy-10-methoxy-14-methyl-1,4-dioxa-14-aza-benzo[j]dispiro[4.2.6.2]hexadec-6-en-13-one 
• 811819-72-4 7-benzyloxy-8-methoxy-12-methyl-12-aza-benzo[h]spiro[5.6]dodec-1-ene-3,11-dione 
• 811819-63-3 3-benzyloxy-2-iodo-4-methoxybenzoic acid 
• 916225-92-8 2-iodo-4-methoxy-3-(methoxymethoxy)benzaldehyde 

Relevant academic research and scientific papers

Total synthesis of (±)-morphine

The morphinan skeleton was effectively synthesized by an intramolecular Mannich-type reaction. Further transformation led to total synthesis of morphine.

Intramolecular Heck cyclization to the galanthamine-type alkaloids: Total synthesis of (±)-lycoramine

A novel approach towards the construction of the galanthamine skeleton was demonstrated by the total synthesis of (±)-lycoramine. The key steps include a Pd-catalyzed intramolecular cyclization to form the seven-membered azepane ring and a spontaneous int