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1-Propionylpiperidin-4-one is a chemical compound with the molecular formula C8H15NO2. It is a derivative of piperidin-4-one, featuring a propionyl group (a three-carbon acyl group) attached to the nitrogen atom. 1-propionylpiperidin-4-one is an important intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly those with piperidine-based structures. Its chemical properties include reactivity towards nucleophiles due to the presence of the carbonyl group, and it can participate in various organic reactions such as condensations, reductions, and substitutions. The compound is typically synthesized through the reaction of piperidin-4-one with propionyl chloride or a related propionylating agent. Its applications span across the fields of medicine, as it can be used to create compounds with analgesic, anti-inflammatory, and sedative properties, as well as in the development of pesticides and other chemical products.

91623-91-5

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91623-91-5 Usage

Drug class

Synthetic opioids

Derivative of

Opioid prodine

Structural similarity

Fentanyl and other synthetic opioids

Effects

Powerful synthetic opioid, stimulant, analgesic

Addictive potential

Highly addictive

Danger potential

Potentially dangerous

Legal status in the United States

Schedule I controlled substance

Legal restrictions

Illegal to manufacture, distribute, or possess (except for authorized research)

International regulation

Strictly regulated in many countries

Overdose potential

Potential for abuse and overdose

Check Digit Verification of cas no

The CAS Registry Mumber 91623-91-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,6,2 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 91623-91:
(7*9)+(6*1)+(5*6)+(4*2)+(3*3)+(2*9)+(1*1)=135
135 % 10 = 5
So 91623-91-5 is a valid CAS Registry Number.

91623-91-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-propionyl-4-piperidone

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:91623-91-5 SDS

91623-91-5Relevant academic research and scientific papers

4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs

Manetti, Dina,Martini, Elisabetta,Ghelardini, Carla,Dei, Silvia,Galeotti, Nicoletta,Guandalini, Luca,Romanelli, Maria Novella,Scapecchi, Serena,Teodori, Elisabetta,Bartolini, Alessandro,Gualtieri, Fulvio

, p. 2303 - 2306 (2007/10/03)

Extrusion of one of the nitrogens of the piperazine ring of potent nootropic drugs previously described gave 4-aminopiperidine analogues that maintained high cognition enhancing activity in the mouse passive avoidance test. One of the new compounds (9, active at 0.01 mg/kg ip) may represent a new lead for the development of cognition enhancers useful to treat the cognitive deficit produced by neurodegenerative pathologies like Alzheimer's disease.

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