916325-86-5Relevant articles and documents
SUBSTITUTED BENZIMIDAZOLES AS POTASSIUM CHANNEL INHIBITORS
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Page/Page column 55; 56, (2019/03/05)
The present invention relates to a compound of the general formula (I). The compounds of formula I are useful for treatment of a cardiac disease, disorder or condition in a mammal.
Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents
Lin, Ronghui,Connolly, Peter J.,Lu, Yanhua,Chiu, George,Li, Shengjian,Yu, Yang,Huang, Shenlin,Li, Xun,Emanuel, Stuart L.,Middleton, Steven A.,Gruninger, Robert H.,Adams, Mary,Fuentes-Pesquera, Angel R.,Greenberger, Lee M.
, p. 4297 - 4302 (2008/02/11)
A series of 3,5-disubstituted pyrazolo[3,4-b]pyridine cyclin-dependent kinase (CDK) inhibitors was synthesized. These compounds showed potent and selective CDK inhibitory activities and inhibited in vitro cellular proliferation in cultured human tumor cel