916332-83-7Relevant academic research and scientific papers
Lanthanide triflate-catalyzed preparation of β,β- difluorohomopropargyl alcohols in aqueous media. Application to the synthesis of 4,4-difluoroisochromans
Arimitsu, Satoru,Hammond, Gerald B.
, p. 8665 - 8668 (2006)
An indium-mediated Barbier-type reaction of difluoropropargyl bromide with several aldehydes in aqueous media was enhanced by a catalytic amount of a lanthanide triflate (5 mol %). The reaction gave the corresponding β,β-difluorohomopropargyl alcohols wit
Supported gold nanoparticles catalyzed: Cis -selective semihydrogenation of alkynes using ammonium formate as the reductant
Liang, Shengzong,Hammond, Gerald B.,Xu, Bo
, p. 6013 - 6016 (2016/05/24)
TiO2 supported gold nanoparticles with low loading (0.5 mol%) are able to semihydrogenate non-fluorinated and gem-difluorinated alkynes to cis-alkenes with high selectivity, using cost-effective and easy-to-handle ammonium formate as the reductant. No over-reduction was observed. The good recyclability of Au/TiO2 allows for "green" semireduction of alkynes. A difluorinated pyran and α,β-unsaturated δ-lactone were easily prepared from the obtained gem-difluoro alkene building blocks.
gem-Difluoropropargylation of aldehydes using cat. In/Zn in aqueous media
Arimitsu, Satoru,Jacobsen, Jesse M.,Hammond, Gerald B.
, p. 1625 - 1627 (2008/02/03)
Zn (0.9 equiv) in combination with catalytic amounts of In (0.1 equiv) and I2 (0.1 equiv) was found to effect the reaction of several difluoropropargyl bromide derivatives with aldehydes to produce gem-difluorohomopropargyl alcohols in aqueous
