91641-92-8Relevant academic research and scientific papers
Catalytic reductive N-alkylation of anilines. Application to the synthesis of N-aryl aminoacid precursors
Fache, Fabienne,Valot, Frederic,Milenkovic, Alexandra,Lemaire, Marc
, p. 9777 - 9784 (1996)
Different anilines have been monoalkylated by reductive alkylation using ketones and α-ketoesters as alkylating agents with good isolated yields. This provided access to aminoacid derivatives. Diastereoselective experiments were also performed.
