916686-40-3Relevant academic research and scientific papers
Liquid-phase split-type combinatorial synthesis of tripeptide derivatives encoded by fluorous fmoc reagents
Sugiyama, Yuya,Hirose, Masaki,Matsui, Junko,Endo, Natsuki,Hamamoto, Hiromi,Shioiri, Takayuki,Matsugi, Masato
, p. 2701 - 2704 (2013)
A liquid-phase mixture synthesis of 18 tripeptides, some of which are analogues of ACE inhibitors, was effectively conducted by using fluorous Fmoc reagents as encoding tags. Georg Thieme Verlag Stuttgart New York.
Fluorous Mixture Synthesis of Tripeptides and Pentapeptides Using- a Fluorous-Fmoc Protection Strategy
Sugiyama, Yuya,Shirai, Ryuhei,Hirose, Masaki,Watanabe, Tomoko,Yoshida, Ayana,Endo, Natsuki,Hayashi, Toshiya,Shioiri, Takayuki,Matsugi, Masato
supporting information, p. 2187 - 2204 (2017/05/05)
A liquid-phase split-type synthesis of various tripeptides and pentapeptides was conducted using a fluorous-Fmoc protection strategy. Fluorous-Fmoc reagents were effectively used as both the protecting group for the amino function and the encoding tag for the amino acid structure. Several of the synthetic peptides prepared showed high activities in an ACE inhibitory assay.
