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2-Bromo-6-chloro-3-nitropyridine, a nitropyridine derivative with the molecular formula C5H3BrClN2O2, is a chemical compound featuring bromine and chlorine substituents on the pyridine ring. It is recognized for its versatility in organic synthesis due to its capacity to participate in a range of chemical reactions such as substitution, addition, and reduction. This makes it a valuable intermediate in the production of pharmaceuticals, agrochemicals, and dyes. However, it is also acknowledged as a potential environmental contaminant, necessitating careful handling and disposal.

91678-23-8

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91678-23-8 Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-6-chloro-3-nitropyridine is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs due to its chemical reactivity and structural properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Bromo-6-chloro-3-nitropyridine serves as an intermediate for the production of pesticides and other agrochemicals, leveraging its ability to form a variety of compounds with potential pesticidal activity.
Used in Dye Industry:
2-BROMO-6-CHLORO-3-NITROPYRIDINE is utilized as an intermediate in the synthesis of dyes, where its unique structure and reactivity allow for the creation of a range of colored compounds used in various applications.
Used in Organic Synthesis:
2-Bromo-6-chloro-3-nitropyridine is employed as a versatile building block in organic synthesis, taking advantage of its capacity to undergo multiple types of chemical reactions to form diverse organic compounds.
Environmental Considerations:
Given its potential as an environmental contaminant, 2-Bromo-6-chloro-3-nitropyridine requires careful handling and disposal to mitigate any adverse effects on the environment, emphasizing the need for responsible practices in its use and management.

Check Digit Verification of cas no

The CAS Registry Mumber 91678-23-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,6,7 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 91678-23:
(7*9)+(6*1)+(5*6)+(4*7)+(3*8)+(2*2)+(1*3)=158
158 % 10 = 8
So 91678-23-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H2BrClN2O2/c6-5-3(9(10)11)1-2-4(7)8-5/h1-2H

91678-23-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Bromo-6-chloro-3-nitropyridine

1.2 Other means of identification

Product number -
Other names 2-BROMO-6-CHLORO-3-NITROPYRIDINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:91678-23-8 SDS

91678-23-8Relevant articles and documents

Organic electroluminescent material and device thereof

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Paragraph 0126-0129, (2020/09/30)

Disclosed are an organic electroluminescent material and a device thereof. The organic electroluminescent material is a novel triaryl amine-aza-carbazole quinazoline compound. The compound is used asa host material in an electroluminescent device and prov

A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors

Bronner, Sarah M.,Murray, Jeremy,Romero, F. Anthony,Lai, Kwong Wah,Tsui, Vickie,Cyr, Patrick,Beresini, Maureen H.,De Leon Boenig, Gladys,Chen, Zhongguo,Choo, Edna F.,Clark, Kevin R.,Crawford, Terry D.,Jayaram, Hariharan,Kaufman, Susan,Li, Ruina,Li, Yingjie,Liao, Jiangpeng,Liang, Xiaorong,Liu, Wenfeng,Ly, Justin,Maher, Jonathan,Wai, John,Wang, Fei,Zheng, Aijun,Zhu, Xiaoyu,Magnuson, Steven

, p. 10151 - 10171 (2018/01/10)

The epigenetic regulator CBP/P300 presents a novel therapeutic target for oncology. Previously, we disclosed the development of potent and selective CBP bromodomain inhibitors by first identifying pharmacophores that bind the KAc region and then building into the LPF shelf. Herein, we report the "hybridization" of a variety of KAc-binding fragments with a tetrahydroquinoline scaffold that makes optimal interactions with the LPF shelf, imparting enhanced potency and selectivity to the hybridized ligand. To demonstrate the utility of our hybridization approach, two analogues containing unique Asn binders and the optimized tetrahydroquinoline moiety were rapidly optimized to yield single-digit nanomolar inhibitors of CBP with exquisite selectivity over BRD4(1) and the broader bromodomain family.

ALKYNYL ALCOHOLS AND METHODS OF USE

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Paragraph 0575; 0576, (2015/03/04)

The invention relates to compounds of Formula (0): wherein A1-A8, R4 and R5 each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.

ALKYNYL ALCOHOLS AND METHODS OF USE

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Page/Page column 142, (2015/03/13)

The invention relates to compounds of Formula (0): wherein A1-A8, R4 and R5 each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.

Heterobicyclic amide compounds

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Page/Page column 10, (2010/11/28)

Compounds of formula I processes for their preparation and pharmaceutical compositions comprising them.

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