916830-69-8

Basic information

• Product Name: (S)-4-(2-trifluoromethylphenyl)pyrrolidin-2-one
• Synonyms: (S)-4-(2-trifluoromethylphenyl)pyrrolidin-2-one
• CAS NO: 916830-69-8
• Molecular Weight: 229.202
• Mol File: 916830-69-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-4-(2-trifluoromethylphenyl)pyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-(2-trifluoromethylphenyl)pyrrolidin-2-one(916830-69-8)
• EPA Substance Registry System: (S)-4-(2-trifluoromethylphenyl)pyrrolidin-2-one(916830-69-8)

Safety Data

• Hazardous Substances Data: 916830-69-8(Hazardous Substances Data)

Upstream product

• 1032199-09-9 methyl (S)-4-nitro-3-(2-trifluoromethylphenyl)butyrate 
• 916830-77-8 methyl (S)-2-oxo-4-(2-trifluoromethylphenyl)pyrrolidine-3-carboxylate 
• 916830-67-6 (S)-4-isopropyl-3-[(S)-4-nitro-3-(2-trifluoromethylphenyl)butyryl]-5,5-diphenyloxazolidin-2-one 

Downstream Products

• 916830-71-2 (S)-3-(2-(trifluoromethyl)phenyl)pyrrolidine 
• 916830-79-0 (S)-3-(2-trifluoromethylphenyl)pyrrolidine hydrochloride 

Relevant articles and documents

METHOD FOR PRODUCING PYRROLIDINE COMPOUND

Provided is a method capable of efficiently producing a compound having a superior HSD1 inhibitory action and a compound useful as a synthetic intermediate therefor, with superior achievability of asymmetric synthesis (i.e., superior selectivity), superior yield, superior safety and superior industrial workability at a low cost. A method of producing a compound represented by the following formula [8]: or a salt thereof, or a solvate thereof, from a compound represented by the following formula [2]: or a reactive derivative thereof, or a salt thereof, or a solvate thereof.