916907-17-0

Upstream product

• 916907-15-8 4-(2-chloro-5-methoxyphenyl)-8-methylsulfanyl-1,2-dihydro-3a,7,9,9b-tetraazacyclopenta[a]naphthalen-3-one 
• 16153-81-4 4-(4-Methyl-piperazino)-anilin 
• 909095-74-5 5-bromomethyl-4-chloro-2-(methylthio)pyrimidine 
• 916907-13-6 1-(2-chloro-5-methoxyphenyl)-2-(4-chloro-2-methylsulfanylpyrimidin-5-yl)ethanone 
• 916907-14-7 1-{5-[2-(2-chloro-5-methoxyphenyl)-2-oxoethyl]-2-methylsulfanylpyrimidin-4-yl}pyrazolidin-3-one 
• 61044-96-0 4-chloro-5-methyl-2-(methylsulfanyl)pyrimidine 

Relevant academic research and scientific papers

Synthesis of novel pyrimido[4,5-c]pyridazines and 1,2-dihydro-3a,7,9,9b-tetraaza-cyclopenta[a]naphthalen-3-ones as potent inhibitors of lymphocyte specific kinase (LCK)

This paper details the synthesis of a novel class of 1,2-dihydro-pyrimido[4,5-c]pyridazines and substituted 1,2-dihydro-3a,7,9,9b-tetraaza-cyclopenta[a]naphthalen-3-one. The most potent analogs disclosed showed low nanomolar activity for the inhibition of