916994-56-4

Upstream product

• 88328-13-6 (E)-N-phenylmethylene-1-(2-pyridyl)methanamine 
• 3731-51-9 2-(Aminomethyl)pyridine 
• 100-52-7 benzaldehyde 
• 2227-79-4 benzenecarbothioamide 

Downstream Products

• 1244553-95-4 2-phenyl-4-(2-pyridyl) thiazole 
• 35854-46-7 3-phenylimidazo[1,5-a]pyridine 
• 52095-67-7 bis(3-phenylimidazo[1,5-a]pyridine-1-yl)sulfide 

Relevant academic research and scientific papers

An Efficient Heterobimetallic Lanthanide Alkoxide Catalyst for Transamidation of Amides under Solvent-Free Conditions

A practical heterobimetallic lanthanide-catalyzed transamidation of primary, secondary and tertiary amides with aliphatic and aromatic amines has been developed. The methodology was also applied to the weakly reactive thioamides to demonstrate its versatility and wide substrate scope. The heterobimetallic lanthanide catalysts showed high catalytic activity and a wide scope of substrates with good to excellent yields under solvent-free conditions. Efficient activation of the transamidation can be realized by the above complexes acting as cooperative acid–base bifunctional catalysts, which are proposed to be responsible for the higher reactivity in comparison with simple monometallic catalysts. (Figure presented.).

THIAZOLE DERIVATIVE AND PROCESS FOR PRODUCING SAME

An object is to provide a thiazole derivative produced from easily available raw materials by a simplified production process. Provided are a process for producing a novel thiazole derivative represented by the general formula (I), which is characterized by adding a strong base to a thioamide represented by the general formula (II) and reacting the mixture with a thioformamide represented by the general formula (III), and a novel thiazole derivative.

Synthesis of 2-azaindolizines by using an iodine-mediated oxidative desulfurization promoted cyclization of N-2-pyridylmethyl thioamides and an investigation of their photophysical properties

Iodine-mediated, oxidative desulfurization promoted cyclization of N-2-pyridylmethyl thioamides serves as an efficient and versatile method for the preparation of 2-azaindolizines (imidazo[1,5-a]pyridines) and rare 2-azaindolizine sulfur-bridged dimers. T