917077-71-5Relevant academic research and scientific papers
Mobilizing Cu(I) for carbon-carbon bond forming catalysis in the presence of thiolate. Chemical mimicking of metallothioneins
Zhang, Zhihui,Lindale, Matthew G.,Liebeskind, Lanny S.
supporting information; experimental part, p. 6403 - 6410 (2011/06/19)
Copper(I) is rendered catalytically viable in the presence of thiolate by the design of a small molecule chemical analogue of the metallothionein system in which an N-O reactant serves the same conceptual purpose of the S-S reactant of the biological system.
Biotinylated biphenyl ketone-containing 2,4-dioxobutanoic acids designed as HIV-1 integrase photoaffinity ligands
Zhao, Xue Zhi,Semenova, Elena A.,Liao, Chenzhong,Nicklaus, Marc,Pommier, Yves,Burke Jr., Terrence R.
, p. 7816 - 7825 (2007/10/03)
The diketo acid (DKA) class of HIV-1 integrase inhibitors are thought to function by chelating divalent metal ions within the enzyme catalytic center. However, differences in mutations conferring resistance among sub-families of DKA inhibitors suggest tha
