917364-07-9

Basic information

• Product Name: 5-chloro-3-phenyl-2-(4-{[4-(4H-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-1,6-naphthyridine
• Synonyms: 5-chloro-3-phenyl-2-(4-{[4-(4H-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-1,6-naphthyridine
• CAS NO: 917364-07-9
• Molecular Weight: 481
• Mol File: 917364-07-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-chloro-3-phenyl-2-(4-{[4-(4H-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-1,6-naphthyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-3-phenyl-2-(4-{[4-(4H-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-1,6-naphthyridine(917364-07-9)
• EPA Substance Registry System: 5-chloro-3-phenyl-2-(4-{[4-(4H-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-1,6-naphthyridine(917364-07-9)

Safety Data

• Hazardous Substances Data: 917364-07-9(Hazardous Substances Data)

Upstream product

• 893424-25-4 4-(1H-1,2,4-triazol-3-yl)piperidine 
• 917363-90-7 4-(5-chloro-3-phenyl-[1,6]naphthyridin-2-yl)-benzaldehyde 
• 105-07-7 4-cyanobenzaldehyde 
• 66739-89-7 4-(1,3-dioxolan-2-yl)benzonitrile 
• 868280-61-9 1-[4-(1,3-dioxolan-2-yl)phenyl]-2-phenylethanone 
• 14432-12-3 4-Amino-2-chloropyridine 
• 234108-73-7 (2-chloro-pyridin-4-yl)-carbamic acid tert-butyl ester 
• 893424-27-6 benzyl 4-(1H-1,2,4-triazol-3-yl)piperidine-1-carboxylate 
• 893423-62-6 tert-butyl (2-chloro-3-formylpyridin-4-yl)carbamate 
• 161609-84-3 4-cyanopiperidine-1-carboxylic acid benzyl ester 

Downstream Products

• 917364-08-0 5-hydrazino-3-phenyl-2-(4-{[4-(4H-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-1,6-naphthyridine 

Relevant articles and documents

INHIBITORS OF AKT ACTIVITY

The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.