917473-28-0

Basic information

• Product Name: 8-(4-methoxy-phenyl)-6-methyl-3-(4-piperidin-1-yl-but-1-ynyl)-5,6,7,8-tetrahydro-[1,6]naphthyridine
• Synonyms: 8-(4-methoxy-phenyl)-6-methyl-3-(4-piperidin-1-yl-but-1-ynyl)-5,6,7,8-tetrahydro-[1,6]naphthyridine
• CAS NO: 917473-28-0
• Molecular Weight: 389.541
• Mol File: 917473-28-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-(4-methoxy-phenyl)-6-methyl-3-(4-piperidin-1-yl-but-1-ynyl)-5,6,7,8-tetrahydro-[1,6]naphthyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(4-methoxy-phenyl)-6-methyl-3-(4-piperidin-1-yl-but-1-ynyl)-5,6,7,8-tetrahydro-[1,6]naphthyridine(917473-28-0)
• EPA Substance Registry System: 8-(4-methoxy-phenyl)-6-methyl-3-(4-piperidin-1-yl-but-1-ynyl)-5,6,7,8-tetrahydro-[1,6]naphthyridine(917473-28-0)

Safety Data

• Hazardous Substances Data: 917473-28-0(Hazardous Substances Data)

Upstream product

• 104612-36-4 5-bromo-2-hydroxynicotinic acid 
• 29241-65-4 5-bromo-2-chloronicotinic acid 
• 609-71-2 2-hydroxy-3-carboxypyridine 
• 917473-38-2 (5-bromo-2-chloropyridin-3-yl)methyl methanesulfonate 
• 742100-75-0 (5-bromo-2-chloro-pyridin-3-yl)-methanol 
• 917473-41-7 3-bromo-8-(4-methoxy-phenyl)-6-methyl-5,8-dihydro-6H-[1,6]naphthyridin-7-one 
• 917473-40-6 N-(5-bromo-2-chloro-pyridin-3-ylmethyl)-2-(4-methoxy-phenyl)-N-methyl-acetamide 
• 917473-39-3 (5-bromo-2-chloro-pyridin-3-ylmethyl)-methyl-amine 
• 917473-42-8 3-bromo-8-(4-methoxy-phenyl)-6-methyl-5,6,7,8-tetrahydro-[1,6]naphthyridine 
• 14256-74-7 1-but-3-ynyl-piperidine 

Downstream Products

• 917473-30-4 8-(4-methoxy-phenyl)-6-methyl-3-(4-piperidin-1-yl-butyl)-5,6,7,8-tetrahydro-[1,6]-naphthyridine 

Relevant articles and documents

Novel naphthyridines are histamine H3 antagonists and serotonin reuptake transporter inhibitors

A series of novel tetrahydronaphthyridine-based histamine H3 ligands that have serotonin reuptake transporter inhibitor activity is described. The 1,2,3,4-tetrahydro-2,6-naphthyridine scaffold is assembled via the addition of a nitrostyrene to a metalated pyridine followed by reduction and cyclization to form the naphthyridine. In vitro biological data for these novel compounds are discussed.