917805-74-4

Basic information

• Product Name: (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid-2-methylpropan-2-amine
• Synonyms: (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid-2-methylpropan-2-amine
• CAS NO: 917805-74-4
• Molecular Weight: 554.683
• Mol File: 917805-74-4.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid-2-methylpropan-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid-2-methylpropan-2-amine(917805-74-4)
• EPA Substance Registry System: (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid-2-methylpropan-2-amine(917805-74-4)

Safety Data

• Hazardous Substances Data: 917805-74-4(Hazardous Substances Data)

Usage

General Description

The chemical compound "(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid-2-methylpropan-2-amine" is a complex molecule containing a pyrimidine ring, a fluorophenyl group, a methylsulfonyl group, and a 3,5-dihydroxyhept-6-enoic acid chain. It also has a 2-methylpropan-2-amine side chain. The compound has multiple functional groups and stereochemistry, making it a challenging molecule to synthesize and study. It may have potential biological activity and could be used in pharmaceutical research or drug development.

Upstream product

• 75-64-9 tert-butylamine 
• 147118-40-9 (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid methyl ester 
• 851443-04-4 ethyl (3R),(5S),(6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxy-6-heptenoate 
• 1364244-32-5 5-O-(triphenylmethyl)-3-deoxy-1,2-anhydro-D-erythro-pentitol 
• 1364244-34-7 (3S,5S)-3,5-dihydroxy-6-(trityloxy)hexanenitrile 
• 2782-09-4 D-arabinono-1,4-lactone 
• 808163-04-4 isopropyl 2-[(4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate 
• 808163-02-2 isopropyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate 
• 808162-99-4 isopropyl 2-[(4R,6S)-6-{(E)-2-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl]vinyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 
• 1364244-19-8 5-O-(triphenylmethyl)-D-arabinono-1,4-lactone 
• 1364244-21-2 5-O-(triphenylmethyl)-3-deoxy-2-O-(methanesulfonyl)-D-glyceropent-2-enono-1,4-lactone 
• 147118-39-6 methyl (3R,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3-hydroxy-5-oxohept-6-enoate 
• 851440-19-2 2-[(4R,6S)-6-[(E)-2-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(isopropyl)pyrimidin-5-yl]vinyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetic acid methyl ester 
• 124655-09-0 1,1-dimethylethyl (4R-cis)-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate 

Downstream Products

• 287714-41-4 rosuvastatin 

Relevant articles and documents

Method for the preparation of high purity Rosuvastatin Calcium salt

The present invention relates to a method for manufacturing a Rosuvastatin calcium salt by using a Rosuvastatin tert-butyl amine salt, and to a method for manufacturing a high purity Rosuvastatin calcium salt, which has impurities less than 0.1% of a diastereomer. The manufacturing method of a high purity Rosuvastatin calcium salt comprises the steps of: 1) manufacturing a compound represented by chemical formula III by reducing a compound represented by chemical formula IV; 2) manufacturing a compound represented by chemical formula II by adding t-butyl amine; and 3) manufacturing a compound represented by chemical formula I by adding a calcium ion to the compound represented by chemical formula II.COPYRIGHT KIPO 2016

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