917807-18-2

Usage

Uses

Used in Pharmaceutical Industry:
2H-Thiopyran-4-carboxylic acid, tetrahydro-, methyl ester, 1,1-dioxide is used as a building block in the synthesis of various pharmaceuticals. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2H-Thiopyran-4-carboxylic acid, tetrahydro-, methyl ester, 1,1-dioxide is used as a precursor for the synthesis of agrochemicals. Its reactivity and chemical properties make it suitable for the development of new pesticides and other agrochemical products.
It is important to handle 2H-Thiopyran-4-carboxylic acid, tetrahydro-, methyl ester, 1,1-dioxide with care, as it may have potential health and environmental hazards. Proper safety measures should be taken during its synthesis, storage, and use to minimize any risks associated with 2H-Thiopyran-4-carboxylic acid, tetrahydro-, methyl ester, 1,1-dioxide.

Upstream product

• 128094-82-6 tetrahydro-thiopyran-4-carboxylic acid methyl ester 
• 195503-40-3 tetrahydro-2H-thiopyrane-4-carbonitrile 
• 89489-53-2 tetrahydro-2H-thiopyran-4-carboxylic acid 

Downstream Products

• 64096-87-3 1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-carboxylic acid 
• 473254-28-3 (1,1-dioxo-hexahydro-1-thiopyran-4-yl)-methanol 
• 1010836-46-0 methanesulfonic acid (1,1-dioxo-hexahydro-1-thiopyran-4-yl)methyl ester 

Relevant academic research and scientific papers

4,6-SUBSTITUTED-PYRAZOLO[1,5-a]PYRAZINES AS JANUS KINASE INHIBITORS

Compounds of Formula I: and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R1, R2, R3 and R4 have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of JAK kinase-associated diseases and disorders, such as autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.

PHENYL ACETAMIDE DERIVATIVE

[Problems] To provide a compound which is useful as a GK activator. [Means for Solving Problems] The present inventors have conducted extensive studies on a phenylacetamide derivative, and as a result, have confirmed that a phenylacetamide derivative having sulfonyl group and cycloalkyl group on the phenyl group and having heteroaryl group on the nitrogen atom in the amide has an excellent GK activation action, thereby completing the present invention. The compound of the present invention is useful as an agent for treating diabetes, in particular, type II diabetes, since it has an excellent GK activation action.

TRIAZOLYLPIPERIDINE DERIVATIVES AND USE THEREOF IN THERAPY

The present invention provides compounds of formula (I) Wherein R1 , R2, R3 , R4 , Het and m are as defined in the description. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors.