917899-14-0

Basic information

• Product Name: Benzenemethanol, a-(aminomethyl)-4-chloro-a-(4-iodophenyl)-
• CAS NO: 917899-14-0
• Molecular Formula: C14H13ClINO
• Molecular Weight: 373.621
• Mol File: 917899-14-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-(aminomethyl)-4-chloro-a-(4-iodophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-(aminomethyl)-4-chloro-a-(4-iodophenyl)-(917899-14-0)
• EPA Substance Registry System: Benzenemethanol, a-(aminomethyl)-4-chloro-a-(4-iodophenyl)-(917899-14-0)

Safety Data

• Hazardous Substances Data: 917899-14-0(Hazardous Substances Data)

Upstream product

• 99847-42-4 (4-chlorophenyl)(4-iodophenyl)methanone 
• 857532-00-4 (RS)-2-(4-chloro-phenyl)-2-(4-iodo-phenyl)-oxirane 

Downstream Products

• 857532-13-9 2-amino-1-(4-chloro-phenyl)-1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol 
• 1056901-67-7 (R)-2-amino-1-(4-chloro-phenyl)-1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol 
• 1056901-62-2 ((1S)-2-amino-1-(4-chlorophenyl)-1-[4-(1H-pyrazol-4-yl)phenyl]ethanol) 
• 1056901-64-4 2-(4-chloro-phenyl)-2-hydroxy-2-[4-(1H-pyrazol-4-yl)-phenyl]-ethyl-carbamic acid tert-butyl ester 
• 1056901-63-3 [2-(4-chloro-phenyl)-2-hydroxy-2-(4-iodo-phenyl)ethyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

PHARMACEUTICAL COMPOUNDS

The invention provides a composition comprising (S) 2-amino-1-(4-chloro-phenyl)- 1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol, wherein the composition is either substantially free of (R) 2-amino-1-(4-chloro-phenyl)-1-[4-(1H-pyrazol-4-yl)- phenyl]-ethanol or the composition contains a mixture of the (S) and (R) enantiomers in which the (S) enantiomer predominates. Also provided are processes for the preparation of the (S) 2-amino-1-(4-chloro-phenyl)-1-[4-(1H- pyrazol-4-yl)-phenyl]-ethanol, novel process intermediates and methods for making the novel process intermediates.