99847-42-4

Usage

Uses

Used in Pharmaceutical Industry:
4-CHLORO-4'-IODOBENZOPHENONE is used as a building block in the synthesis of pharmaceuticals for its versatile chemical structure, which can be further modified to create various medicinal compounds.
Used in Agrochemical Industry:
4-CHLORO-4'-IODOBENZOPHENONE is used as a building block in the synthesis of agrochemicals, contributing to the development of new pesticides and other agricultural products.
Used in Organic Compounds Synthesis:
4-CHLORO-4'-IODOBENZOPHENONE is used as a building block for the synthesis of other organic compounds, owing to its unique structure that allows for a wide range of chemical reactions and modifications.

InChI:InChI=1/C13H8ClIO/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8H

Upstream product

• 108-90-7 chlorobenzene 
• 1711-02-0 4-iodobenzoic acid chloride 
• 106-39-8 bromochlorobenzene 
• 24167-53-1 4-iodo-N,N-dimethylbenzamide 
• 51934-41-9 4-iodobenzoic acid ethyl ester 

Downstream Products

• 92044-37-6 4-Chlor-4'-iod-diphenylmethan 
• 917899-60-6 3-(4-chloro-phenyl)-3-hydroxy-3-(4-iodo-phenyl)propionitrile 
• 857532-14-0 2-[2-(4-chloro-phenyl)-2-hydroxy-2-(4-iodo-phenyl)-ethyl]-isoindole-1,3-dione 
• 857532-01-5 1-(4-chloro-phenyl)-2-(2-hydroxy-ethylamino)-1-(4-iodo-phenyl)-ethanol 
• 857532-02-6 2-(4-chloro-phenyl)-2-(4-iodo-phenyl)-morpholine 
• 1056901-66-6 (RS)-2-ammonio-1-(4-chlorophenyl)-1-(4-iodophenyl)ethanol toluene-4-sulphonate 
• 1056901-64-4 2-(4-chloro-phenyl)-2-hydroxy-2-[4-(1H-pyrazol-4-yl)-phenyl]-ethyl-carbamic acid tert-butyl ester 
• 1056901-63-3 [2-(4-chloro-phenyl)-2-hydroxy-2-(4-iodo-phenyl)ethyl]-carbamic acid tert-butyl ester 
• 1056901-65-5 (RS)-2-azido-1-(4-chlorophenyl)-1-(4-iodophenyl)ethanol 
• 917899-14-0 2-amino-1-(4-chloro-phenyl)-1-(4-iodo-phenyl)-ethanol 
• 857532-13-9 2-amino-1-(4-chloro-phenyl)-1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol 
• 857532-00-4 (RS)-2-(4-chloro-phenyl)-2-(4-iodo-phenyl)-oxirane 
• 172219-25-9 ethyl 1-<2-<(4-chlorophenyl)(4-iodophenyl)>methoxyethyl>piperidine-4-carboxylate 
• 172219-26-0 <2-<(4-chlorophenyl)(4-iodophenyl)>methoxyethyl>-1-piperidine-3-carboxylic acid 

Relevant academic research and scientific papers

Continuous Flow Acylation of (Hetero)aryllithiums with Polyfunctional N,N-Dimethylamides and Tetramethylurea in Toluene

The continuous flow reaction of various aryl or heteroaryl bromides in toluene in the presence of THF (1.0 equiv) with sec-BuLi (1.1 equiv) provided at 25 °C within 40 sec the corresponding aryllithiums which were acylated with various functionalized N,N-

Synthesis of [2-{(4-chlorophenyl)(4-[125I]iodophenyl)} methoxyethyl]-1-piperidine-3-carboxylic acid, [125I]CIPCA: A potential radiotracer for GABA uptake sites

The synthesis of racemic [2-{(4-Chlorophenyl)(4-iodophenyl)} methoxyethyl]-1-piperidine-3-carboxylic acid, (CIPCA) and its radioiodinated analog [125]CIPCA is described. CIPCA was synthesized from 4-iodobenzoyl chloride in five steps in 16% overall yield. Ammonium sulfate catalyzed solid-state isotopic exchange of CIPCA with Na125I provided [125I]CIPCA in 34% isolated radiochemical yield at a specific activity of 118 Ci/mmol. [125I]CIPCA demonstrated moderate brain extraction and good in vivo radiostability in preliminary biodistribution studies conducted in CD-1 mice. [125I]CIPCA is a potentially useful radiotracer for study of the GABA uptake system.