91806-19-8Relevant articles and documents
Traceless solid phase synthesis of 2-substituted pyrimidines using an 'off-the-shelf' chlorogermane-functionalised resin
Spivey, Alan C.,Srikaran, Ratnasothy,Diaper, Christopher M.,Turner, David J.
, p. 1638 - 1640 (2007/10/03)
The parallel solid phase synthesis of an 18-member library of 2-substituted pyrimidines is described using a chlorogermane-functionalised resin. The success of the key Pinner-type condensations between a resin-bound enaminone and an array of amidine hydrochlorides highlights the stability of arylgermane linkers (cf. arylsilanes) towards strongly basic/nucleophilic conditions.