918306-87-3Relevant academic research and scientific papers
Synthesis of fused 3-aminoazepinones via trapping of a new class of cyclic seven-membered allenamides with furan
Schurgers, Ben,Brigou, Ben,Urbanczyk-Lipkowska, Zofia,Tourwe, Dirk,Ballet, Steven,De Proft, Frank,Van Lommen, Guy,Verniest, Guido
supporting information, p. 3712 - 3715 (2014/08/05)
Novel tricyclic tetrahydroazepinones were synthesized via an in situ Diels-Alder reaction of furan with cyclic allenamides. These reactive intermediates are the first examples of cyclic seven-membered allenamides and were prepared starting from N-(2-chlor
Synthesis of amino acid derived seven-membered lactams by RCM and their evaluation against HIV protease
Zaman, Shazia,Campaner, Pietro,Abell, Andrew D.
, p. 8323 - 8331 (2008/02/04)
A versatile synthesis of hydroxylated and epoxy 1-azepin 2-ones substituted at N1, C-3 and C-4 or C-7 has been developed. The sequence involves ring-closing metathesis of an amino acid derived diene amide, followed by either epoxidation or dihydroxylation
