91852-97-0Relevant articles and documents
A facile method for the synthesis of thiocarbamates: Palladium-catalyzed reaction of disulfide, amine, and carbon monoxide
Nishiyama, Yutaka,Kawamatsu, Hiroaki,Sonoda, Noboru
, p. 2551 - 2554 (2007/10/03)
(Equation Presented) A new method for the synthesis of thiocarbamates has been developed. When dialkyl or diaryl disulfides were allowed to react with secondary amines and carbon monoxide in the presence of a catalytic amount of a palladium complex, the thiocarbamates were obtained in moderate to good yields. In contrast to that of secondary amines, in the reaction of a primary amine, no formation of thiocarbamate was confirmed, but urea was formed in good yield.
Novel synthesis of S-alkyl thiocarbamates from amines, carbon monoxide, elemental sulfur, and alkyl halides in the presence of a selenium catalyst
Mizuno, Takumi,Nishiguchi, Ikuzo,Sonoda, Noboru
, p. 5669 - 5680 (2007/10/02)
Carbonyl selenide easily reacted with elemental sulfur at low temperature to form carbonyl sulfide in a good yield, and reaction of ammonium salts of selenocarbamates with elemental sulfur brought about ready transformation to those of thiocarbamates. On the basis of the high catalytic activity of selenium for carbonylation of amines with carbon monoxide in addition to these important findings, a convenient new method for synthesis of S-alkyl thiocarbamates was developed through the carbonylation of amines with carbon monoxide and elemental sulfur in the presence of a selenium catalyst under mild conditions followed by alkylation of ammonium salts of the thiocarbamates with alkyl halides.
Facile synthesis of S-alkyl thiocarbamates through reaction of carbamoyl lithium with elemental sulfur
Mizuno, Takumi,Nishiguchi, Ikuzo,Okushi, Tsuneo,Hirashima, Tsuneaki
, p. 6867 - 6868 (2007/10/02)
Efficient synthesis of S-alkyl thiocarbamates was developed. The key step of this synthetic method is a conversion of carbamoyl lithium, generated from lithium dialkylamide and carbon monoxide, to lithium thiocarbamate by addition of elemental sulfur.