91893-83-3 Usage
Description
Garcinoic acid is a derivative of vitamin E originally isolated from C. grandiflora. It inhibits IL-1β-induced microsomal prostaglandin E2 synthase-1 (mPGES-1) activity in A549 cells when used at concentrations of 1 and 10 μM. It has higher antioxidant activity relative to (±)-α-tocopherol in a cell-free assay when used at a concentration of 0.15 mM.
Uses
Garcinoic Acid displays anti-angiogenic activity as well as anti-oxidative activity in animals.
General Description
Natural product derived from plant source.
Check Digit Verification of cas no
The CAS Registry Mumber 91893-83-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,8,9 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 91893-83:
(7*9)+(6*1)+(5*8)+(4*9)+(3*3)+(2*8)+(1*3)=173
173 % 10 = 3
So 91893-83-3 is a valid CAS Registry Number.
91893-83-3Relevant articles and documents
A stereocontrolled synthesis of δ-trans-tocotrienoloic acid
Maloney, David J.,Hecht, Sidney M.
, p. 4297 - 4300 (2005)
(Chemical Equation Presented) A consise stereoselective total synthesis of a naturally occurring polymerase β inhibitor, δ-trans-tocotrienoloic acid (2), is described. The key step in the synthesis is an acid-catalyzed cyclodehydration reaction. Additiona
