91906-19-3

Basic information

• Product Name: 2-(2,5-dimethoxy-3,4,6-trimethylphenyl)ethanol
• Synonyms: 2-(2,5-dimethoxy-3,4,6-trimethylphenyl)ethanol
• CAS NO: 91906-19-3
• Molecular Weight: 224.3
• Mol File: 91906-19-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2,5-dimethoxy-3,4,6-trimethylphenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,5-dimethoxy-3,4,6-trimethylphenyl)ethanol(91906-19-3)
• EPA Substance Registry System: 2-(2,5-dimethoxy-3,4,6-trimethylphenyl)ethanol(91906-19-3)

Safety Data

• Hazardous Substances Data: 91906-19-3(Hazardous Substances Data)

Upstream product

• 75-21-8 oxirane 
• 60-29-7 diethyl ether 
• 69821-05-2 1-bromo-2,5-dimethoxy-3,4,6-trimethylbenzene 
• 4537-09-1 1,4-dimethoxy-2,3,5-trimethyl-benzene 
• 67-56-1 methanol 
• 854647-18-0 (2,5-dimethoxy-3,4,6-trimethyl-phenyl)-acetic acid ethyl ester 

Downstream Products

• 84071-98-7 1-(2-bromoethyl)-2,5-dimethoxy-3,4,6-trimethylbenzene 
• 873968-33-3 1-(2-chloro-ethyl)-2,5-dimethoxy-3,4,6-trimethyl-benzene 
• 950-99-2 2,2,5,7,8-pentamethylchroman-6-ol 

Relevant articles and documents

Highly stereoselective construction of the C2 stereocentre of α-tocopherol (Vitamin E) by asymmetric addition of Grignard reagents to ketones

Tertiary alcohol precursors of both C2 diastereoisomers of α-tocopherol were prepared in three ways by our recently reported asymmetric Grignard synthesis. The versatility of Grignard chemistry inherent in its three-way disconnection was exploited to allow the synthesis of three product grades: 77:23 dr (5 steps), 81:19 dr (5 steps) and 96:4 dr (7 steps, one gram scale) from readily available and abundant starting materials. The products were converted to their respective α-tocopherols in 3 steps, which allowed a definitive re-assignment of their absolute configurations.