919282-69-2

Upstream product

• 913263-45-3 C₃₆H₅₄N₂O₆SSi 
• 194599-72-9 N-Cyclopentylmethyl-4-methoxy-N-(R)-1-oxiranylmethyl-benzenesulfonamide 
• 194599-67-2 N-[(S)-3-((S)-3-Benzyl-5-oxo-morpholin-4-yl)-2-hydroxy-propyl]-N-cyclopentylmethyl-4-methoxy-benzenesulfonamide 
• 101250-48-0 (S)-5-benzylmorpholin-3-one 
• 194599-66-1 C₃₃H₅₀N₂O₆SSi 

Downstream Products

• 913263-50-0 C₃₅H₅₄N₂O₇SSi 
• 913263-52-2 C₃₆H₅₆N₂O₉S₂Si 
• 919282-73-8 C₃₅H₅₃N₅O₆SSi 
• 913263-54-4 C₂₉H₃₉N₅O₆S 
• 913263-56-6 C₃₆H₅₃N₃O₆SSi 
• 919282-86-3 C₃₆H₅₅N₃O₇SSi 

Relevant academic research and scientific papers

New, potent P1/P2-morpholinone-based HIV-protease inhibitors

We have developed efficient synthesis of morpholinone-based cyclic mimetics of the P1/P2 portion of the HIV-1 protease inhibitor Amprenavir. This effort led to discovery of allyl- and spiro-cyclopropyl-P2-substituted inhibitors 17 and 31, both 500 times m