91933-71-0

Upstream product

• 1193-82-4 racemic methyl phenyl sulfoxide 
• 70-55-3 toluene-4-sulfonamide 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 4381-25-3 (S)-S-methyl-S-phenylsulfoximine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 102817-13-0 C₂₇H₂₃NO₃S₂ 
• 181268-42-8 (S)-(+)-(E)-S-(hex-1-enyl)-S-phenyl-N-(p-tolylsulfonyl)sulfoximine 
• 180720-13-2 (S)-1-(N-tosyl-S-phenylsulfonimidoyl)methylcyclohexanol 
• 114663-00-2 C₁₅H₁₇NO₃S₂ 
• 102817-20-9 C₁₈H₂₁NO₃S₂ 
• 102817-14-1 (S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine 
• 102817-17-4 C₁₉H₂₃NO₃S₂ 
• 102817-12-9 (S)-S-phenyl-2-<(E)-2-phenylethenyl>-N-<(p-tolyl)sulfonyl>sulfoximid 
• 102817-19-6 (S)-N-tosyl-S-phenyl-S-(1-cyclohex-1-enylmethyl)sulfoximine 
• 102817-22-1 (S)-N-tosyl-S-phenyl-S-(trimethylsilyl)methylsulfoximine 
• 102817-18-5 C₂₃H₂₁NO₃S₂ 
• 1455028-44-0 (1R,2R)-2-(4-fluorophenyl)-N-methoxy-N-methylcyclopropanecarboxamide 
• 1455028-46-2 (1S,2S)-2-(4-fluorophenyl)-N-methoxy-N-methylcyclopropanecarboxamide 

Relevant academic research and scientific papers

Iron-catalyzed imidative kinetic resolution of racemic sulfoxides

Kinetic resolution of racemic sulfoxides requires either custom substrates or shows moderate enantioselectivity, leading to achiral coproducts (such as sulfones) as an intrinsic part of the process. A new strategy is demonstrated that allows the resolution of racemic sulfoxides through catalytic asymmetric nitrene-transfer reactions. This approach gives rise to both optically active sulfoxides and highly enantioenriched sulfoximines. By using a chiral iron catalyst and a readily available iodinane reagent, high selectivity factors have been achieved under very practical reaction conditions. With respect to the substrate scope, it is noteworthy that this unprecedented imidative kinetic resolution of racemic sulfoxides provides access to both aryl-alkyl and dialkyl sulfoximines in highly enantioenriched forms. Copyright

Asymmetric intramolecular Diels-Alder reactions of sulfoximine-activated trienes

A series of N-substituted sulfoximidoyl-1,6,8-nonatrienes and 1,7,9-decatrienes were synthesized and subjected to thermal intramolecular Diels-Alder (IMDA) reactions to give diastereomeric mixtures of substituted bicyclo[4.3.0]nonanes and -[4.4.0]decanes. The reactions showed varying selectivities. Endo/exo selectivity was interpreted in terms of a combination of steric factors and the asynchronous nature of the cycloadditions. Diastereofacial selectivity could be rationalised by considering attack by the diene on the less hindered face of the conformationally extended vinylic sulfoximine dienophile.

Chiral Recognition during the Reaction of Dienyliron Complexes with Sulphoximine-stabilized Enolates

The first example is reported of chiral recognition during enolate nucleophile addition to dienyliron complexes; enantiomeric excesses of up to 50percent were obtained by reaction of complex (1) with enolates derived from the sulphoximinyl ester derivativ