91940-86-2

Usage

Uses

Used in Poultry Farming:
2-Ethoxy-4-pyridinecarboxylic acid is used as a coccidiostat for the prevention and control of coccidiosis in poultry. It functions by inhibiting the enzyme dihydrofolate reductase, which is vital for the synthesis of DNA and RNA in coccidian parasites. This disruption of the parasites' metabolism helps to mitigate the impact of coccidiosis on poultry health and productivity.
Used in Treatment of Protozoan Parasite Diseases:
Ethopabate is also utilized in the treatment of other diseases caused by protozoan parasites in animals. Its ability to interfere with the metabolic processes of these parasites contributes to the management and mitigation of infections.
Regulatory Considerations:
The use of 2-Ethoxy-4-pyridinecarboxylic acid is carefully regulated in the industry due to concerns regarding its potential toxicity and the possibility of developing resistant strains of parasites. This highlights the need for responsible and judicious application of ethopabate in veterinary medicine to ensure its continued efficacy and safety.

InChI:InChI=1/C8H9NO3/c1-2-12-7-5-6(8(10)11)3-4-9-7/h3-5H,2H2,1H3,(H,10,11)/p-1

Upstream product

• 6313-54-8 2-chloroisonicotinic acid, 
• 141-52-6 sodium ethanolate 
• 6291-10-7 2-chloro-6-ethoxyisonicotinic acid 
• 64-17-5 ethanol 
• 5398-44-7 2,6-dichloropyridine-4-carboxylic acid 

Downstream Products

• 1131735-06-2 6-{[2,6-dichloro-4-(trifluoromethyl)phenyl]amino}pyrido[4,3-c]-1,6-naphthyridin-10(9H)-one 
• 1131735-05-1 6-{[2-fluoro-6-(trifluoromethyl)phenyl]amino}pyrido[4,3-c]-1,6-naphthyridin-10(9H)-one 
• 1131736-89-4 C₁₉H₁₄Cl₂N₄O₂ 
• 1131735-21-1 6-{[2,6-dichloro-4-(1-hydroxy-1-methylethyl)phenyl]amino}pyrido[4,3-c]-1,6-naphthyridin-10(9H)-one 
• 1581260-52-7 C₁₉H₁₂Cl₂F₂N₄O₂ 
• 1131735-94-8 {4-[(diisopropylamino)carbonyl]-2-ethoxypyridin-3-yl}boronic acid 
• 1131736-56-5 N-(2-chloro-4,6-difluorophenyl)-10-ethoxypyrido[4,3-c]-1,6-naphthyridin-6-amine 
• 1581260-54-9 C₁₉H₁₃F₃N₄O 
• 1581260-55-0 C₁₉H₁₃Cl₂FN₄O 
• 1581260-57-2 C₂₀H₁₃Cl₂F₃N₄O₂ 
• 1581260-58-3 C₂₀H₁₃Cl₂F₃N₄O 
• 1581260-59-4 C₂₀H₁₄F₄N₄O 
• 1131736-58-7 10-chloro-N-(2-chloro-4,6-difluorophenyl)pyrido[4,3-c]-1,6-naphthyridin-6-amine 
• 1581260-62-9 C₁₇H₈ClF₃N₄ 

Relevant academic research and scientific papers

Spiro derivative, preparation method thereof and application of spiro derivative in medicine

The invention relates to a spiro derivative, a preparation method thereof and application of the spiro derivative in medicine. Specifically, the invention relates to the spiro derivative shown in a general formula (I), the preparation method thereof, a pharmaceutical composition containing the spiro derivative and application of the spiro derivative as a therapeutic agent, especially application of the spiro derivative as an RAF inhibitor and application of the spiro derivative in preparation of drugs for treating or preventing various diseases (including cancers) related to over-expression RAF activity.