91950-62-8

Basic information

• Product Name: methanesulfonic acid 2-(toluene-4-sulfonyl)-ethyl ester
• Synonyms: methanesulfonic acid 2-(toluene-4-sulfonyl)-ethyl ester
• CAS NO: 91950-62-8
• Molecular Weight: 278.35
• Mol File: 91950-62-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methanesulfonic acid 2-(toluene-4-sulfonyl)-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: methanesulfonic acid 2-(toluene-4-sulfonyl)-ethyl ester(91950-62-8)
• EPA Substance Registry System: methanesulfonic acid 2-(toluene-4-sulfonyl)-ethyl ester(91950-62-8)

Safety Data

• Hazardous Substances Data: 91950-62-8(Hazardous Substances Data)

Upstream product

• 13290-16-9 2-(p-tolylthio)-ethanol 
• 824-79-3 sodium 4-methylbenzenesulfinate 

Downstream Products

• 1015247-42-3 8-tert-butyl-3-(2-tosylethyl)-1,3-diazaspiro[4,5]decane-2,4-dione 
• 852615-11-3 5-(tert-butyl-diphenyl-silanyloxymethyl)-3-(3,4-dimethoxy-benzyl)-8b-hydroxy-7-(toluene-4-sulfonyl)-1-[2-(toluene-4-sulfonyl)-ethyl]-8-triisopropylsilanyloxymethyl-1,3,5,5a,7,8,8a,8b-octahydro-imidazo[4,5-e]isoindole-2,6-dione 
• 852615-10-2 5-(tert-butyl-diphenyl-silanyloxymethyl)-3-(3,4-dimethoxy-benzyl)-7-(toluene-4-sulfonyl)-1-[2-(toluene-4-sulfonyl)-ethyl]-8-triisopropylsilanyloxymethyl-1,3,4,5,5a,7,8,8a-octahydro-imidazo[4,5-e]isoindole-2,6-dione 
• 852615-26-0 3-{3-(3,4-dimethoxybenzyl)-2-oxo-1-[2-(toluene-4-sulfonyl)-ethyl]-2,3-dihydro-1H-imidazol-4-yl}-acrylic acid ethyl ester 
• 852615-07-7 3-(3,4-dimethoxybenzyl)-4-(3-hydroxypropenyl)-1-[2-(toluene-4-sulfonyl)-ethyl]-1,3-dihydro-imidazol-2-one 
• 852615-23-7 3-(3,4-dimethoxybenzyl)-2-oxo-1-[2-(toluene-4-sulfonyl)-ethyl]-2,3-dihydro-1H-imidazole-4-carboxylic acid methyl ester 
• 852615-24-8 3-(3,4-dimethoxybenzyl)-4-(hydroxymethyl)-1-[2-(toluene-4-sulfonyl)-ethyl]-1,3-dihydro-imidazol-2-one 
• 852615-25-9 3-(3,4-dimethoxybenzyl)-2-oxo-1-[2-(toluene-4-sulfonyl)-ethyl]-2,3-dihydro-1H-imidazole-4-carbaldehyde 
• 852615-22-6 2-oxo-1-[2-(toluene-4-sulfonyl)-ethyl]-2,3-dihydro-1H-imidazole-4-carboxylic acid methyl ester 
• 91062-32-7 4-(2-methanesulfonyloxy-ethanesulfonyl)-benzoic acid 

Relevant articles and documents

A unified synthetic strategy toward oroidin-derived alkaloids premised on a biosynthetic proposal

Details of the evolution of a synthetic strategy toward the spirocyclic chlorocyclopentane core of oroidin-derived alkaloids, including the axinellamines and potentially adaptable to palau'amine, are described. A proposed refinement of the Kinnel-Scheuer biosynthetic proposal for palau'amine is posited. Studies undertaken to improve the regioselectivity and efficiency of a key Diels-Alder reaction utilizing a novel protecting group strategy, microwave chemistry, and other strategies are described. Further insights regarding the suitability of different protecting groups during the epoxidation/chlorination/ring contraction sequence are disclosed. Several interesting by-products from this reaction sequence are reported. These studies have led to a unified synthetic strategy to the axinellamines and palau'amine.