919530-62-4Relevant academic research and scientific papers
Synthesis of DNA strands site-specifically damaged by C8-arylamine purine adducts and effects on various DNA polymerases
Boege, Nicolas,Jacobsen, Maike I.,Szombati, Zita,Baerns, Sabrina,Di Pasquale, Francesca,Marx, Andreas,Meier, Chris
experimental part, p. 11194 - 11208 (2009/11/30)
C8-Arylamine-dG and C8-arylamine-dA adducts have been prepared using palladium cross-coupling chemistry. These adducts were subsequently converted into the corresponding 5′-O-DMTr-C8-arylamine-3′-O-phosphoramidites and then used for the automated synthesi
Synthesis of DNA-oligonucleotides damaged by arylamine-modified 2′-deoxyguanosine
Boege,Szombati,Meier
, p. 705 - 708 (2008/09/17)
C8-Arylamine-dG adducts bearing a labile N-formamidine group at the exocyclic amino function were converted into their corresponding 5′-O-DMTr-3′-O-phosphoramidite-C8-arylamine-dG derivatives. These compounds were used for the automated synthesis of site-
Synthesis and properties of oligonucleotides containing C8-deoxyguanosine arylamine adducts of borderline carcinogens
Boege, Nicolas,Graesl, Sonja,Meier, Chris
, p. 9728 - 9738 (2007/10/03)
C8-Arylamine-dG adducts of borderline carcinogens and the bladder and breast carcinogen 4-aminobiphenyl were prepared using cross-coupling chemistry. These adducts were converted into the corresponding C8-arylamine-5′-O- DMTr-2′-deoxyguanosine phosphorami
A practical approach for the chemical synthesis of 2′-deoxyguanosine-C8 adducts with mutagenic/carcinogenic amino- or nitro-arenes
Takamura-Enya, Takeji,Ishikawa, Satoko,Mochizuki, Masataka,Wakabayashi, Keiji
, p. 5969 - 5973 (2007/10/03)
Synthetic methods for the preparation of 2′-deoxyguanosine-C8 (dG-C8) adducts with several mutagenic and carcinogenic amino- or nitro-arenes were developed using the palladium-mediated cross-coupling reaction of protected 8-amino-dG with bromoarenes in ar
