91973-60-3

Upstream product

• 3326-71-4 2-furoic acid hydrazide 
• 100-52-7 benzaldehyde 
• 88-14-2 2-furanoic acid 
• 611-13-2 2-furoic acid methyl ester 

Downstream Products

• 1258067-83-2 dimethyl 2-[N'-benzylidene-N-(2-furanoyl)hydrazino]-3-(cyclohexyliminomethylene)succinate 
• 1258067-84-3 dimethyl 2-[N'-benzylidene-N-(2-furanoyl)hydrazino]-3-(tert-butyliminomethylene)succinate 
• 180971-38-4 Cu(C₁₂H₉N₂O₂)2 
• 14093-97-1 2-(furan-2-yl)-5-phenyl-1,3,4-oxadiazole 
• 180971-42-0 [Ni(C₁₂H₉N₂O₂)(H₂O)2Cl]2 

Relevant academic research and scientific papers

Antiparasitic activity of furanyl N-acylhydrazone derivatives against Trichomonas vaginalis: In vitro and in silico analyses

Background: Trichomonas vaginalis is the causative agent of trichomoniasis, which is one of the most common sexually transmitted diseases worldwide. Trichomoniasis has a high incidence and prevalence and is associated with serious complications such as HI

Di- and Tetranuclear Palladium(II) Complexes Containing C,N-Bidentate Furoylhydrazone for Suzuki–Miyaura Reactions

Furoylhydrazones of general formula 4-R–C6H4–CH=NNH–CO–2-C4H3O [R = H (HL1) and OCH3 (HL2)] have been conveniently prepared from furan-2-carbohydrazide. The reaction of HL1 with Li2[PdClsu

Study on DDQ-promoted synthesis of 2, 5-disubstituted 1, 3, 4-oxadiazoles from acid hydrazides and aldehydes

A facile stepwise synthesis of 2, 5-disubstituted 1, 3, 4-oxadiazoles proceeding via oxidative cyclization of N-acylhydrazones is reported. The reaction is efficiently promoted by 2, 3-dichloro-5, 6-dicyano-1, 4- benzoquinone (DDQ) to afford the desired products mostly in high yields and in relatively short times. The final 1, 3, 4-oxadiazole derivatives are also synthesized directly from acid hydrazides and aldehydes in a one-pot procedure. The substrate scope and limitations of the reported transformation are discussed in detail.

Metal-Free Synthesis of 1,3,4-Oxadiazoles from N′-(Arylmethyl)hydrazides or 1-(Arylmethyl)-2-(arylmethylene)hydrazines

An efficient and versatile metal-free synthesis of 1,3,4-oxadiazoles from N′-(arylmethyl)hydrazides or 1-(arylmethyl)-2-(arylmethylene)hydrazines through oxidative dehydrogenation is reported. A range of 2,5-disubstituted 1,3,4-oxadiazoles were prepared by treating N′-(arylmethyl)hydrazides with (diacetoxyiodo)benzene in acetonitrile or by treating 1-(arylmethyl)-2-(arylmethylene)hydrazines with [bis(trifluoroacetoxy)iodo]benzene in methyl tert-butyl ether. Aldehyde N-acylhydrazones and aldazines were initially generated in situ as intermediates.

Efficient oxidative cyclisation of acid hydrazides to 2,5-disubstituted 1,3,4-oxadiazoles catalysed by Bu4NI with t-BuOOH as oxidant

Acid hydrazides or araldehyde N-acylhydrazones can be converted in good yields to, respectively, symmetrical or unsymmetrical, 2,5-disubstituted 1,3,4-oxadiazoles at 60 °C by a Bu4NI-catalysed procedure which requires the presence of a base and 2.5 equiv. of t-butyl hydroperoxide.

USE OF DYNAMIC MIXTURES FOR A CONTROLLED RELEASE OF FRAGRANCES

The present invention relates to a delivery system in the form of a dynamic mixture obtained by reacting together, in the presence of water, at least one hydrazine derivative with at least one perfuming, flavoring, insect repellent or attractant, bactericide and/or fungicide aldehyde or ketone. The invention's mixture is capable of releasing in a controlled and prolonged manner said aldehyde or ketone in the surrounding environment. Furthermore, the present invention concerns also the use of said dynamic mixtures as perfuming ingredients as well as the perfuming compositions or perfumed articles comprising the invention's mixtures.