92020-81-0

Basic information

• Product Name: 3-chloro-1-(4-methyl-3,4-dihydroquinolin-1(2H)-yl)propan-1-one
• CAS NO: 92020-81-0
• Molecular Formula: C₁₃H₁₆ClNO
• Molecular Weight: 237.7252
• Mol File: 92020-81-0.mol

Chemical Properties

• Boiling Point: 400.6°C at 760 mmHg
• Flash Point: 196.1°C
• Density: 1.151g/cm³
• Vapor Pressure: 1.26E-06mmHg at 25°C
• Refractive Index: 1.546
• CAS DataBase Reference: 3-chloro-1-(4-methyl-3,4-dihydroquinolin-1(2H)-yl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-1-(4-methyl-3,4-dihydroquinolin-1(2H)-yl)propan-1-one(92020-81-0)
• EPA Substance Registry System: 3-chloro-1-(4-methyl-3,4-dihydroquinolin-1(2H)-yl)propan-1-one(92020-81-0)

Safety Data

• Hazardous Substances Data: 92020-81-0(Hazardous Substances Data)

Upstream product

• 19343-78-3 4-methyl-1,2,3,4-tetrahydroquinoline 
• 625-36-5 2-chloropropionyl chloride 
• 491-35-0 C₆H₄NCH₂CHCCH₂ 

Downstream Products

• 105847-59-4 1-hydroxy-1-methyl-1,2,6,7-tetrahydropyrido<3,2,1-i,j>quinolin-5(3H)-one 

Relevant articles and documents

Microbiological Transformations, Part 9. Microbiological Transformations of 1,2,5,6-Tetrahydropyrroloquinolin-4-one and of Derivatives of 1,2,3,5,6,7-Hexahydropyridoquinoline with the Fungus Cunninghamella elegans

Incubation of 1,2,6,7-tetrahydropyridoquinolin-3(5H)-one with C. elegans resulted in oxidation at the C-7 benzylic position, whereas 1-methyl-1,2,6,7-tetrahydropyridoquinolin-5(3H)-one gave products resulting from oxidation at both benzylic positions. cis- and trans-1-Hydroxy-3-methyl-1,2,6,7-tetrahydropyridoquinolin-5(3H)-ones were produced on incubation of 5-methyl-1,2,6,7-tetrahydropyridoquinolin-3(5H)-one with C. elegans, in addition to trans-1-hydroxy-5-methyl-1,2,6,7-tetrahydropyridoquinolin-3(5H)-one.Incubation of 1,2,5,6-tetrahydropyrroloquinolin-4-one with C. elegans resulted in dehydrogenation to 1,2-dihydropyrroloquinolin-4-one.Incubation of 2,3,6,7-tetrahydropyridoquinolin-1(5H)-one with C. elegans resulted in benzylic attack at C-7.