92033-25-5

Basic information

• Product Name: C₁₃H₁₈N₂O₂
• CAS NO: 92033-25-5
• Molecular Weight: 234.298
• Mol File: 92033-25-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₈N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₈N₂O₂(92033-25-5)
• EPA Substance Registry System: C₁₃H₁₈N₂O₂(92033-25-5)

Safety Data

• Hazardous Substances Data: 92033-25-5(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 50461-74-0 ethyl 2-oxovalerate 
• 62-53-3 aniline 
• 1540-28-9 ethyl 2-propylacetoacetate 

Downstream Products

• 92287-88-2 3-ethyl-1H-indole-2-carboxylic acid 
• 69472-67-9 ethyl 3-ethyl-1H-indole-2-carboxylate 
• 1377838-15-7 3-ethyl-N-(2-(4-(piperidin-1-yl)phenyl)ethyl)-1H-indole-2-carboxamide 

Relevant articles and documents

Indole-2-carboxamides as allosteric modulators of the cannabinoid CB 1 receptor

We synthesized new N-phenylethyl-1H-indole-2-carboxamides as the first SAR study of allosteric modulators of the CB1 receptor. The presence of the carboxamide functionality was required in order to obtain a stimulatory effect. The maximum stimulatory activity on CB1 was exerted by carboxamides 13 (EC50 = 50 nM) and 21 (EC50 = 90 nM) bearing a dimethylamino or piperidinyl group, respectively, at position 4 of the phenethyl moiety and a chlorine atom at position 5 of the indole.