50461-74-0

Basic information

• Product Name: Ethyl 2-oxovalerate
• Synonyms: Ethyl 2-oxovalerate;2-OXO-PENTANOIC ACID ETHYL ESTER;Ethyl-2-oxo-pentanoate;2-OXO-PENTAROIC ACID ETHYL ESTER;2-Oxovalericacidethylester;2-OXO-PENTAROIC ACID ETHYL ESTER, >95%;PENTANOICACID,2-OXO-,ETHYLESTER;2-Oxyvaleric acid ethyl ester
• CAS NO: 50461-74-0
• Molecular Formula: C₇H₁₂O₃
• Molecular Weight: 144.17
• EINECS: 256-593-3
• Product Categories: API
• Mol File: 50461-74-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 182.5°C (estimate)
• Flash Point: 71.4 °C
• Appearance: Light yellow oil liquid
• Density: 0.9985
• Vapor Pressure: 0.808mmHg at 25°C
• Refractive Index: 1.4170
• Storage Temp.: 2-8°C
• Solubility: Chloroform, DMSO, Methanol
• CAS DataBase Reference: Ethyl 2-oxovalerate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-oxovalerate(50461-74-0)
• EPA Substance Registry System: Ethyl 2-oxovalerate(50461-74-0)

Safety Data

• Hazardous Substances Data: 50461-74-0(Hazardous Substances Data)

Usage

Uses

Ethyl 2-oxopentanoate is used as a reagent to synthesize selective CB1 cannabinoid receptor antagonists. Ethyl 2-oxopentanoate is also used to synthesize derivatives of iminodiacid, an inhibitor of angiotensin converting enzyme.

InChI:InChI=1/C7H12O3/c1-3-5-6(8)7(9)10-4-2/h3-5H2,1-2H3

Upstream product

• 26103-77-5 2-Ethyl-3-oxo-succinic acid diethyl ester 
• 3249-68-1 ethyl butyroyl acetate 
• 79584-44-4 Ethyl 2-azido pentanoate 
• 64-17-5 ethanol 
• 1821-02-9 2-oxopentanoic acid 
• 927-77-5 n-propylmagnesium bromide 
• 95-92-1 oxalic acid diethyl ester 
• 69461-35-4 N-(1-oxo-1-aethoxy-2-pentyl)-N-phenyl-N-trifluormethansulfonamid 
• 14273-07-5 1-ethoxy-pent-1-yne 
• 615-83-8 2-bromo-pentanoic acid ethyl ester 
• 615-79-2 ethyl 2,4-diketopentanoate 

Downstream Products

• 92033-25-5 2-phenylhydrazono-valeric acid ethyl ester 
• 129546-84-5 (E)-ethyl 2-[2-(4-nitrophenyl)hydrazono]pentanoate 
• 13074-61-8 2-propylmaleic acid 
• 5469-28-3 n-propylfumaric acid 
• 5796-70-3 2-propylidenesuccinic acid 
• 200286-28-8 2-Oxo-3-phenylselanyl-pentanoic acid ethyl ester 
• 88945-70-4 ethyl 2-hydroxy-n-valerate 
• 110038-75-0 2-propyltetrahydroquinoxaline 
• 178041-62-8 3,4-dihydro-3-propyl-1H-quinoxalin-2-one 
• 1361569-68-7 4-amino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-6-propylpteridin-7(8H)-one 
• 122454-52-8 (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid benzyl ester 
• 82834-16-0 Perindopril 
• 129546-85-6 Ethyl 2-(4-nitrophenylhydrazono)valerat 
• 145513-54-8 1-<(2S) 2-<((1S) 1-carbethoxybutyl) amino> 1-oxo propyl> (2S, 3aS, 7aS) perhydroindole 2-carboxylic acid 

Relevant articles and documents

MICROCAPSULES CONTAINING A GAS-GENERATING PHOTOLABILE KETOACID OR KETOESTER AND USES THEREOF

The present invention relates to water-dispersable microcapsules comprising an oil phase, e.g. a perfume, containing a photolabile α-ketoacid or α-ketoester capable of generating a gas upon exposure to light. The gas is able to cause an extension or the breaking of the microcapsule allowing the release of the oil phase and thus increasing the long-lastingness of the odor perception. The present invention concerns also the use of said microcapsules in perfumery as well as the perfuming compositions or perfumed articles comprising the invention's microcapsules to provide a prolonged release of fragrant molecules.

HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE

The present invention relates to a compound represented by a formula (I): wherein X is a group represented by or the like; Y is a group represented by or the like; and Ar1 is a group represented by or a pharmaceutically acceptable salt thereof.

PROCESS FOR PREPARING a-KETO ACIDS AND DERIVATIVES THEREOF

A method for preparing α-keto acids, especially α-ketomethionine, and/or derivatives thereof, whereby an aldehyde is reacted with thiols to give a corresponding dithioacetal, the dithioacetal formed, is reacted with an electrophile in the presence of a strong base, and the resulting α,α-(dithio)carboxylic acid is solvolyzed with acid-catalysis to release thiol and give the α-keto acid or a derivative thereof. Umpolung of aliphatic or aromatic aldehydes is effected by reaction with thiols.