920449-57-6

Basic information

• Product Name: Thiophene, 2-(2,4,6-trimethylphenyl)-
• CAS NO: 920449-57-6
• Molecular Formula: C13H14S
• Molecular Weight: 202.32
• Mol File: 920449-57-6.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Thiophene, 2-(2,4,6-trimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiophene, 2-(2,4,6-trimethylphenyl)-(920449-57-6)
• EPA Substance Registry System: Thiophene, 2-(2,4,6-trimethylphenyl)-(920449-57-6)

Safety Data

• Hazardous Substances Data: 920449-57-6(Hazardous Substances Data)

Upstream product

• 576-83-0 2,4,6-trimethylphenyl bromide 
• 15106-95-3 bis(thien-2-yl)zinc 
• 73681-65-9 bis(2,4,6-trimethylphenyl)-zinc 
• 1003-09-4 2-bromothiophene 
• 123-91-1 1,4-dioxane 
• 13780-71-7 dihydroxyborane 
• 5980-97-2 mesitylboronic acid 
• 96-43-5 2-thienyl chloride 
• 2633-66-1 2-mesitylmagnesium bromide 
• 5713-61-1 thiophen-2-yl magnesium bromide 

Downstream Products

• 1416896-32-6 C₆₉H₅₂S 

Relevant articles and documents

BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION CATALYSTS WITH CHAIN TRANSFER CAPABILITY

Catalyst systems that include a chain transfer agent and a metal-ligand complex according to formula (I).

Synthesis of heteroaryl compounds through cross-coupling reaction of aryl bromides or benzyl halides with thienyl and pyridyl aluminum reagents

An efficient method for synthesis of useful biaryl building blocks containing 2-thienyl, 3-thienyl, 2-pyridyl, and 3-pyridyl moieties was provided through cross-coupling reactions of aryl bromides or benzyl halides with heteroaryl aluminum reagents in the presence of Pd(OAc)2 and (o-tolyl)3P. The coupling reaction also worked efficiently with heteroaryl bromides affording series of heterobiaryl compounds. The reaction of phenylbromide with in situ prepared 3-pyridyl aluminum was demonstrated to afford the product 8a in high yield. Additionally, the catalytic system was also suited well for the coupling reaction of benzyl halides with pyridyl aluminum reagents to afford series of pyridyl-arylmethane.

Kumada-Tamao-Corriu coupling of heteroaromatic chlorides and aryl ethers catalyzed by (IPr)Ni(allyl)Cl

The complex (IPr)Ni(allyl)Cl (IPr = 1,3-bis(2,6-diisopropylphenyl) imidazolidene) catalyzes the cross-coupling reactions of heteroaromatic chlorides with aryl Grignard reagents. Catalyst loadings as low as 0.1 mol % have been used to afford the products in excellent yields. This nickel-based catalytic system also promotes the activation of the CAr-O bond of anisoles in the Kumada-Tamao-Corriu reaction under fairly mild conditions.