92188-49-3Relevant academic research and scientific papers
2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases
Schnute, Mark E.,Anderson, David J.,Brideau, Roger J.,Ciske, Fred L.,Collier, Sarah A.,Cudahy, Michele M.,Eggen, MariJean,Genin, Michael J.,Hopkins, Todd A.,Judge, Thomas M.,Kim, Euibong J.,Knechtel, Mary L.,Nair, Sajiv K.,Nieman, James A.,Oien, Nancee L.,Scott, Allen,Tanis, Steven P.,Vaillancourt, Valerie A.,Wathen, Michael W.,Wieber, Janet L.
, p. 3349 - 3353 (2008/02/07)
A novel series of 2-aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potent antivirals against human herpesviruses. These compounds demonstrate broad-spectrum inhibition of the herpesvirus polymerases HCMV, HSV-1, EBV, and VZV with high specificity compared to human DNA polymerases.
ARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS
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Page 35, (2010/02/06)
The present invention provides a compound of formula as describedherein, which are useful as antiviral agents, in particular, as agents against viruses of the herpes family.
Pyridoquinoxaline antivirals
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, (2008/06/13)
The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof wherein R1, R2 and R3 are as defined in the specification. The compounds are useful for the treatment of viral infections.
