92289-37-7

Upstream product

• 19349-84-9 3-phenylamino-4-nitropyridine N-oxide 
• 62-53-3 aniline 
• 1678-49-5 3-Bromo-4-nitropyridine N-oxide 

Downstream Products

• 1189641-96-0 N-(3-phenylamino-4-pyridinyl)3,3,3-trifluoropropanesulfonamide 
• 1189641-81-3 N-(3-phenylamino-4-pyridinyl)methanesulfonamide 
• 1580455-99-7 N-(cyclopropylsulfonyl)-N-[(3-phenylamino)pyridin-4-yl]cyclopropanesulfonamide 
• 1580456-00-3 N-[3-(phenylamino)pyridin-4-yl]cyclopropanesulfonamide 

Relevant academic research and scientific papers

IMIDAZOPYRIDINE DERIVATIVES AS PI3K INHIBITORS

New imidazopyridine derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).

Pyridine analogues of nimesulide: Design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors

Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most prescribed medications, although the chronic use of such pharmacological agents is commonly associated with numerous side effects. The demonstration that the use of COX-2 selective or

Design, synthesis, and pharmacological evaluation of pyridinic analogues of nimesulide as cyclooxygenase-2 selective inhibitors

In this study, we report the synthesis and pharmacological evaluation of original pyridinic sulfonamides related to nimesulide, a cyclooxygenase-2 (COX-2) preferential inhibitor widely used as an anti-inflammatory agent. These original pyridinic derivativ