923032-76-2

Upstream product

• 923032-74-0 3,4-difluoro-N₂-(2-fluoro-4-iodo-phenyl)-6-methoxy-benzene-1,2-diamine 
• 530-62-1 1,1'-carbonyldiimidazole 
• 923032-72-8 (2,3-difluoro-5-methoxy-6-nitro-phenyl)-(2-fluoro-4-iodo-phenyl)-amine 
• 765962-71-8 (2-fluoro-4-iodo-phenyl)-(2,3,5-trifluoro-6-nitro-phenyl)-amine 
• 314-41-0 1,2,3,5-tetrafluoro-4-nitrobenzene 
• 29632-74-4 2-fluro-4-iodoaniline 

Downstream Products

• 1224119-84-9 1-(cyclopropylsulfonyl)-4,5-difluoro-3-(2-fluoro-4-iodophenyl)-7-methoxy-1H-benzo[d]imidazol-2(3H)-one 
• 1311401-10-1 6,7-difluoro-1-(2-fluoro-4-iodophenyl)-4-methoxy-5-nitro-1,3-dihydrobenzoimidazol-2-one 
• 1311401-13-4 5-amino-6,7-difluoro-1-(2-fluoro-4-iodophenyl)-4-methoxy-1,3-dihydrobenzoimidazol-2-one 
• 1311401-19-0 5-amino-6,7-difluoro-1-(2-fluoro-4-iodophenyl)-4-hydroxy-1,3-dihydrobenzoimidazol-2-one 
• 1311401-28-1 4,5-difluoro-6-(2-fIuoro-4-iodophenyl)-6,8-dihydroimidazo[4',5':3,4]benzo[1,2-d]oxazol-7-one 
• 1311401-48-5 8-cyclopropanesulfonyl-4,5-difluoro-6-(2-fluoro-4-iodophenyl)-6,8-dihydroimidazo[4',5':3,4]benzo[1,2-d]oxazol-7-one 
• 1311400-85-7 cyclopropanesulfonic acid [4,5-difluoro-6-(2-fluoro-4-iodophenylamino)-benzooxazol-7-yl]amide 

Relevant academic research and scientific papers

HETEROCYCLIC SULFONAMIDE DERIVATIVES

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The compounds have been demonstrated as inhibitors of MEK and therefore may be useful in the treatment of hyperproliferative diseases (e.g., cancer and inflammation).

N-(ARYLAMINO)-SULFONAMIDE INHIBITORS OF MEK

This invention concerns N-(2-arylamino) aryl sulfonamides, which are inhibitors of MEK and are useful in treatment of cancer and other hyperproliferative diseases.