923170-94-9

Basic information

• Product Name: 1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol
• Synonyms: 1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol
• CAS NO: 923170-94-9
• Molecular Formula: C10H9F3O3
• Molecular Weight: 234.1718696
• Mol File: 923170-94-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol(923170-94-9)
• EPA Substance Registry System: 1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol(923170-94-9)

Safety Data

• Hazardous Substances Data: 923170-94-9(Hazardous Substances Data)

Usage

General Description

1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol is a chemical compound with a molecular formula C10H9F3O3. It is a trifluoroethanol derivative that contains a benzodioxin ring system. 1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol is commonly used as a building block for the synthesis of pharmaceuticals and agrochemicals. It has potential applications in medicinal chemistry and drug discovery due to its unique molecular structure and its ability to participate in various chemical reactions. Additionally, its trifluoroethanol moiety provides it with solubility in both organic solvents and water, which can be advantageous in synthetic processes and in the development of pharmaceutical formulations.

Upstream product

• 29668-44-8 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 1400691-55-5 C₉H₁₆N₂*C₃H₂F₆O₂ 

Downstream Products

• 122243-34-9 1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethan-1-one 

Relevant articles and documents

Highly efficient synthesis of aryl and heteroaryl trifluoromethyl ketones via o-iodobenzoic acid (IBX)

A two-step process for the synthesis of aryl and heteroaryl trifluoromethyl ketones from the corresponding aldehydes is described. Trifluoromethyl alcohols were prepared from aryl and heteroaryl aldehydes in excellent yields using catalytic amount of K2CO3. The trifluoromethyl alcohols were then oxidized conveniently and efficiently by o-iodoxybenzoic acid (IBX) under mild conditions to get the desired functionalized aryl and heteroaryl trifluoromethyl ketones.

NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING INHIBITORY EFFECT ON PRODUCTION OF KYNURENINE

The present invention provides a nitrogen-containing heterocyclic compound or a pharmaceutically acceptable salt thereof having an inhibitory effect on the production of kynurenine, represented by formula (I): (wherein R6 and R7 may be the same or different and each represent a hydrogen atom or the like, R8, R9, R19, and R11 may be the same or different and each represent a hydrogen atom or the like, R1 represents lower alkyl which may be substituted with cycloalkyl, or the like, and R3 represents optionally substituted aryl or an optionally substituted heterocyclic group).