92419-65-3

Upstream product

• 108-31-6 maleic anhydride 
• 2216-51-5 (-)-menthol 
• 34212-60-7 di-<(1R,2S,5R)-(-)-menthyl>maleate 

Downstream Products

• 81177-19-7 mono-(-)-menthyl fumaric acid 
• 942913-35-1 (1R,2S,5R)-(-)-menthyl 3-chloroformylacrylate 
• 116440-64-3 (1S,2S,3S,4R)-3-Benzyloxycarbonylamino-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 116440-64-3 (1S,2R,3S,4R)-3-Benzyloxycarbonylamino-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 116440-67-6 (1S,2S)-4,5-Dimethyl-cyclohex-4-ene-1,2-dicarboxylic acid 1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl) ester 2-((R)-methoxycarbonyl-phenyl-methyl) ester 
• 116415-21-5 (1R,2S,3S,4S)-3-(Toluene-4-sulfonylamino)-bicyclo[2.2.1]heptane-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 116440-65-4 (1S,2S)-4,5-Dimethyl-cyclohex-4-ene-1,2-dicarboxylic acid 1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl) ester 2-((S)-1-phenyl-ethyl) ester 
• 116440-62-1 (E)-But-2-enedioic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester (R)-methoxycarbonyl-phenyl-methyl ester 
• 116415-19-1 (-)-menthyl (-)-phenethyl fumarate 
• 116440-63-2 (2S,3S)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid mono-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl) ester 
• 76529-73-2 (-)-menthyl methyl fumarate 
• 2216-51-5 (-)-menthol 
• 110-16-7 maleic acid 
• 110-17-8 (2E)-but-2-enedioic acid 

Relevant academic research and scientific papers

Diastereoselectivities in the Diels-Alder reactions of cyclopentadiene with optically active dimenthyl fumarate and menthyl methyl fumarate in LiClO4/ether and on Al2O3

Reactions of cyclopentadiene with (-)-dimenthyl fumarate, which yield adducts 1 and 2, and with (-)-menthyl methyl fumarate, which yield adducts 3 through 6, were carried out on alumina activated at different temperatures, in LiClO4/ether solut

IMPROVEMENTS IN OR RELATED TO ORGANIC COMPOUNDS

Malodour counteracting preparations for oral use comprising esterified fumarates of the formula (I) wherein X and Y have the same meaning as given in the description, is disclosed. Furthermore, the invention refers to a process for their preparation and t

Asymmetric Diels-Alder reaction of unsymmetrical maleates. A chemical access to chiral, unsymmetrical cis-cyclohexene-1,2-dicarboxylates

A new route to optically active, unsymmetrical cis-cyclohexene-1,2-dicarboxylate derivatives has been developed on the basis of the asymmetric Diels-Alder reaction of chiral, unsymmetrical maleates catalyzed by certain Lewis acids. A notably high level of asymmetric induction has been observed in the asymmetric Diels-Alder reaction of unsymmetrical maleates possessing chiral auxiliaries such as α-phenethyl and trans-2-phenylcyclohexyl groups. The origin of the chiral outcome using these dienophiles has been elucidated.

ASYMMETRIC DIELS-ALDER REACTION. A FACILE ROUTE TO CHIRAL ALKYL HYDROGEN CYCLOHEXENE-1,2-DICARBOXYLATE

An efficient route to optically active alkyl hydrogen cyclohexene-1,2-dicarboxylate derivatives by means of asymmetric Diels-Alder reaction of rationally modified chiral fumarates is described.

Chiral Induction in Photochemical Reactions, VI. - Asymmetric Control of the Addition of Hemipinacol Radicals to Chiral Maleates and Fumarates

The photocatalysed addition of 2-propanol (2) to the monoesters of maleic acid 1b and 1d yields the esters of terebic acid 5b and 5d with a diastereoselectivity up to 62percent de.The major diastereomer 5d has (2S)-configuration.Diastereoselectivity of 23