924282-31-5

Upstream product

• 79271-56-0 triethylsilyl trifluoromethyl sulfonate 
• 169895-52-7 (E)-3-[(2R,3S,4aR,6R,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-3-hydroxy-2-methyl-octahydro-pyrano[3,2-b]pyran-2-yl]-acrylic acid methyl ester 

Downstream Products

• 924282-39-3 3-[2-methyl-3-triethylsilanyloxy-8-triisopropylsilanyloxy-6-(3-triisopropylsilanyloxy-propyl)-octahydro-pyrano[3,2-b]pyran-2-yl]-propionic acid 2-(tert-butyl-dimethyl-silanyloxy)-2-methyl-1-[3-(2,4,6-trichloro-benzyloxy)-propyl]-but-3-enyl ester 
• 924282-43-9 8-{2-(tert-butyl-dimethyl-silanyloxy)-2-methyl-1-[3-(2,4,6-trichloro-benzyloxy)-propyl]-but-3-enyloxy}-5a-methyl-4-triisopropylsilanyloxy-2-(3-triisopropylsilanyloxy-propyl)-9-vinyl-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalene 
• 924282-40-6 3-[3-hydroxy-2-methyl-8-triisopropylsilanyloxy-6-(3-triisopropylsilanyloxy-propyl)-octahydro-pyrano[3,2-b]pyran-2-yl]-propionic acid 2-(tert-butyl-dimethyl-silanyloxy)-2-methyl-1-[3-(2,4,6-trichloro-benzyloxy)-propyl]-but-3-enyl ester 
• 924282-44-0 C₅₅H₉₇Cl₃O₈Si₃ 

Relevant academic research and scientific papers

A convergent approach to the formal total synthesis of hemibrevetoxin B

A convergent synthesis of the key synthetic intermediate of hemibrevetoxin B was achieved via the intramolecular allylation of an α-chloroacetoxy ether and subsequent ring-closing metathesis.

Formal total synthesis of hemibrevetoxin B via the intramolecular allylation followed by ring-closing metathesis

A formal total synthesis of hemibrevetoxin B (1) is described. Intramolecular allylation of α-chloroacetoxy ether 10, prepared from carboxylic acid 11 and alcohol 12, was carried out with MgBr2·OEt2 to give 27. Ring-closing metathesi