924286-01-1

Upstream product

• 924286-00-0 (2S,3R,4S)-3-acryloxy-1-(tert-butyldiphenylsilyloxy)-2,4-dimethylhex-5-ene 
• 92817-88-4 (2S)-3-{[tert-butyl(diphenyl)silyl]oxy}-2-methylpropanal 
• 106357-26-0 1-(tert-butyl-diphenyl-silanyloxy)-2(S),4(S)-dimethyl-hex-5-en-3(R)-ol 
• 95514-03-7 (S)-3-(tert-butyl-diphenyl-silanyloxy)-2-methyl-propionic acid methyl ester 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 95514-04-8 (R)-3-(tert-butyldiphenylsilyloxy)-2-methylpropan-1-ol 

Downstream Products

• 924286-08-8 (2R,5S,6S)-6-[(1S)-2-(p-toluenesulfonyl)-1-methylethyl]-5-methyl-2-methoxy-5,6-dihydro-2H-pyran 
• 924286-48-6 (2R,3S,6S)-6-[(2S,3S,6R)-(6-methoxy-3-methyl-3,6-dihydro-2H-pyran-2-yl)-1-(4-methoxybenzyloxy)]-2-methylheptan-3-ol 
• 924286-15-7 (2S,3S,6S)-6-[(2S,3S,6R)-(6-methoxy-3-methyl-3,6-dihydro-2H-pyran-2-yl)-1-(4-methoxybenzyloxy)]-2-methylheptan-3-ol 
• 924286-65-7 (5S,6S)-6-[(2S,5S,6S)-5-hydroxy-7-(4-methoxybenzyloxy)-6-methylheptan-2-yl]-5-methyl-5,6-dihydropyran-2-one 
• 924286-84-0 6-[4-hydroxy-6-(4-methoxy-benzyloxy)-1,5-dimethyl-hexyl]-5-methyl-5,6-dihydro-2H-pyran-2-ol 
• 934237-11-3 (2S,3S,6R)-2-[(2S,5S,6S)-5-(1-ethoxyethyloxy)-7-(4-methoxybenzyloxy)-6-methylheptan-2-yl]-6-methoxy-3-methyl-3,6-dihydro-2H-pyran 
• 924286-49-7 (2S,3S,6R)-2-[(2S,5S,6R)-5-triethylsilyloxy-7-(4-methoxybenzyloxy)-6-methylheptan-2-yl]-6-methoxy-3-methyl-3,6-dihydro-2H-pyran 
• 924286-66-8 bis[(9H-fluoren-9-yl)methyl](2S,3S,6S)-1-(4-methoxybenzyloxy)-2-methyl-6-((2S,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)heptan-3-yl phosphate 
• 1033231-01-4 (5S,6R)-6-[(1S)-2-(tert-butyl-diphenylsilanyloxy)-1-methyl-ethyl]-5-methyl-5,6-dihydro-2H-pyran-2-ol 
• 924286-07-7 (2R,5S,6S)-6-[(1S)-2-(tert-butyldiphenylsilyloxy)-1-methylethyl]-5-methyl-2-methoxy-5,6-dihydro-2H-pyran 

Relevant academic research and scientific papers

Synthetic studies toward C3-C9 segment of Soraphen A1α

The ring-closure metathesis of the diene (2S,3R,4S)-1-(tert- butyldiphenylsilyloxy)-2,4-dimethylhex-5-en-3-yl acrylate produced the dihydropyrone with the correct stereochemistry for Soraphen A1α synthesis. The C2,C3 stereocenters were introduced by the a

Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: Impact on PP2A inhibition

The total synthesis of cytostatin, an antitumor agent belonging to the fostriecin family of natural products, is described in full detail. The convergent approach relied on a key epoxide-opening reaction to join the two stereotriad units and a single-step

Total synthesis of cytostatin

The total synthesis of cytostatin, an antitumor agent belonging to the fostriecin family of natural products, is disclosed. The convergent route features a key epoxide opening reaction to join the two stereotriad units and a single-step late stage, stereo