934237-11-3

Upstream product

• 924286-15-7 (2S,3S,6S)-6-[(2S,3S,6R)-(6-methoxy-3-methyl-3,6-dihydro-2H-pyran-2-yl)-1-(4-methoxybenzyloxy)]-2-methylheptan-3-ol 
• 109-92-2 ethyl vinyl ether 
• 924286-11-3 (2R,3S)-4-(4-methoxybenzyloxy)-3-methylbutane-1,2-diol 
• 934237-10-2 2-(6-methoxy-3-methyl-3,6-dihydro-2H-pyran-2-yl)-propan-1-ol 
• 924286-09-9 (2S,3R)-3,4-(pentane-3,3-diyl)dioxy-2-methylbutan-1-ol 
• 924286-04-4 (2R,5S,6S)-6-[(1S)-2-iodo-1-methylethyl]-5-methyl-2-methoxy-5,6-dihydro-2H-pyran 
• 924286-05-5 (R)-2-[(S)-1-(4-methoxybenzyloxy)propan-2-yl]oxirane 
• 924286-08-8 (2R,5S,6S)-6-[(1S)-2-(p-toluenesulfonyl)-1-methylethyl]-5-methyl-2-methoxy-5,6-dihydro-2H-pyran 
• 924286-10-2 (R)-2,2-diethyl-4-[(S)-1-(4-methoxybenzyloxy)propan-2-yl]-1,3-dioxolane 
• 924286-07-7 (2R,5S,6S)-6-[(1S)-2-(tert-butyldiphenylsilyloxy)-1-methylethyl]-5-methyl-2-methoxy-5,6-dihydro-2H-pyran 
• 924286-01-1 (5S,6R)-6-[(1S)-2-(tert-butyl-diphenylsilanyloxy)-1-methyl-ethyl]-5-methyl-5,6-dihydro-pyran-2-one 
• 924286-00-0 (2S,3R,4S)-3-acryloxy-1-(tert-butyldiphenylsilyloxy)-2,4-dimethylhex-5-ene 
• 106357-26-0 1-(tert-butyl-diphenyl-silanyloxy)-2(S),4(S)-dimethyl-hex-5-en-3(R)-ol 
• 77333-26-7 (2R,3S)-threo-3-methylbutane-1,2,4-triol 

Relevant academic research and scientific papers

Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: Impact on PP2A inhibition

The total synthesis of cytostatin, an antitumor agent belonging to the fostriecin family of natural products, is described in full detail. The convergent approach relied on a key epoxide-opening reaction to join the two stereotriad units and a single-step

Total synthesis of cytostatin

The total synthesis of cytostatin, an antitumor agent belonging to the fostriecin family of natural products, is disclosed. The convergent route features a key epoxide opening reaction to join the two stereotriad units and a single-step late stage, stereo