92444-99-0 Usage
Uses
Used in Organic Synthesis:
2-CHLORO-5-METHYLPYRIDINE-3-CARBALDEHYDE is used as a building block in organic synthesis for its ability to form a wide range of chemical compounds. Its unique structure allows for the creation of diverse molecules with potential applications in various fields.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2-CHLORO-5-METHYLPYRIDINE-3-CARBALDEHYDE is used as an intermediate in the production of drugs. Its reactivity and structural features make it a valuable component in the synthesis of medicinal compounds, contributing to the development of new therapeutic agents.
Used in Agrochemical Manufacturing:
2-CHLORO-5-METHYLPYRIDINE-3-CARBALDEHYDE also finds application in the agrochemical sector, where it is utilized in the synthesis of pesticides and other agricultural chemicals. Its role in creating effective and targeted agrochemicals is vital for enhancing crop protection and yield.
Used in Research and Drug Development:
As a chemical reagent, 2-CHLORO-5-METHYLPYRIDINE-3-CARBALDEHYDE is employed in research laboratories for the exploration of new chemical reactions and the development of innovative drug candidates. Its presence in experimental settings aids scientists in understanding its properties and potential uses in creating novel compounds.
Used in the Production of Fine Chemicals:
In the fine chemicals industry, 2-CHLORO-5-METHYLPYRIDINE-3-CARBALDEHYDE is used for its ability to contribute to the synthesis of high-quality specialty chemicals. Its versatility and reactivity are essential in producing chemicals with specific properties required for various applications.
It is essential to handle 2-CHLORO-5-METHYLPYRIDINE-3-CARBALDEHYDE with care and to adhere to appropriate safety measures when working with it in laboratory or industrial environments to ensure the safety of personnel and the integrity of the compound.
Check Digit Verification of cas no
The CAS Registry Mumber 92444-99-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,4,4 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 92444-99:
(7*9)+(6*2)+(5*4)+(4*4)+(3*4)+(2*9)+(1*9)=150
150 % 10 = 0
So 92444-99-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H6ClNO/c1-5-2-6(4-10)7(8)9-3-5/h2-4H,1H3
92444-99-0Relevant academic research and scientific papers
Facile and selective synthesis of chloronicotinaldehydes by the Vilsmeier reaction
Gangadasu,Narender,Bharath Kumar,Ravinder,Ananda Rao,Ramesh,China Raju,Jayathirtha Rao
, p. 8398 - 8403 (2007/10/03)
Eleven enamides were prepared by adopting different procedures. The various enamides prepared were subjected to Vilsmeier reaction using (i) POCl3/DMF; (ii) diphosgene/DMF; (iii) triphosgene/DMF leading to the formation of various multisubstituted chloronicotinaldehydes. Studies carried out indicate that Vilsmeier reagent concentration and the replacement of POCl3 by diphosgene or triphosgene, provides excellent selectivity and higher yields. Under modified reaction conditions one can get only chloronicotinaldehydes and not the chloropyridines as products. The various advantages in using diphosgene and triphosgene are illustrated. The mechanism of formation of chloronicotinaldehyde was discussed.
A Versatile New Synthesis of Quinolines and Related Fused Pyridines. Part 12. A General Synthesis of 2-Chloropyridines and 2-Pyridons
Meth-Cohn, Otto,Westwood, Keith T.
, p. 1173 - 1182 (2007/10/02)
The Vilsmeier formylation of tertiary and secondary enamides leads to 2-pyridons and 2-chloropyridines, respectively.The reaction appears to be quite general allowing substitution in the 1-, 3-, 5-, or 6-position or combinations of these.The major limitation arises with enamides which are unsymmetrically substituted on the double bond with alkyl groups, when mixtures can result.Attempts to introduce a 4-substituent by a variation of the Vilsmeier reagent had limited success.
