92444-99-0 Usage
General Description
2-CHLORO-5-METHYLPYRIDINE-3-CARBALDEHYDE is a chemical compound with the molecular formula C7H6ClNO. It is a yellow solid that is commonly used in organic synthesis and as an intermediate in the production of pharmaceuticals and agrochemicals. 2-CHLORO-5-METHYLPYRIDINE-3-CARBALDEHYDE is typically used as a building block in the synthesis of various biologically active molecules and is also employed in the manufacture of other chemical compounds. As a versatile chemical reagent, 2-CHLORO-5-METHYLPYRIDINE-3-CARBALDEHYDE has applications in research, drug development, and the production of fine chemicals. It is important to handle this compound with care and to use appropriate safety precautions when working with it in a laboratory or industrial setting.
Check Digit Verification of cas no
The CAS Registry Mumber 92444-99-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,4,4 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 92444-99:
(7*9)+(6*2)+(5*4)+(4*4)+(3*4)+(2*9)+(1*9)=150
150 % 10 = 0
So 92444-99-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H6ClNO/c1-5-2-6(4-10)7(8)9-3-5/h2-4H,1H3
92444-99-0Relevant articles and documents
Facile and selective synthesis of chloronicotinaldehydes by the Vilsmeier reaction
Gangadasu,Narender,Bharath Kumar,Ravinder,Ananda Rao,Ramesh,China Raju,Jayathirtha Rao
, p. 8398 - 8403 (2007/10/03)
Eleven enamides were prepared by adopting different procedures. The various enamides prepared were subjected to Vilsmeier reaction using (i) POCl3/DMF; (ii) diphosgene/DMF; (iii) triphosgene/DMF leading to the formation of various multisubstituted chloronicotinaldehydes. Studies carried out indicate that Vilsmeier reagent concentration and the replacement of POCl3 by diphosgene or triphosgene, provides excellent selectivity and higher yields. Under modified reaction conditions one can get only chloronicotinaldehydes and not the chloropyridines as products. The various advantages in using diphosgene and triphosgene are illustrated. The mechanism of formation of chloronicotinaldehyde was discussed.
