924646-16-2Relevant academic research and scientific papers
Efficient Preparation of Imidazo[1,5- a ]pyridine-1-carboxylic Acids
Tverdiy, Dmytro O.,Chekanov, Maksym O.,Savitskiy, Pavlo V.,Syniugin, Anatolii R.,Yarmoliuk, Sergiy M.,Fokin, Andrey A.
, p. 4269 - 4277 (2016/11/26)
We report a novel and efficient approach to the synthesis of imidazo[1,5-a]pyridine-1-carboxylic acids. By using the reaction of 2-(aminomethyl)pyridine with acyl chlorides followed by one-pot treatment with trifluoroacetic anhydride, 2,2,2-trifluoro-1-im
Design, synthesis and biological evaluation of imidazo[1,5-a]pyridine-PBD conjugates as potential DNA-directed alkylating agents
Kamal, Ahmed,Ramakrishna,Ramaiah, M. Janaki,Viswanath,Rao, A. V. Subba,Bagul, Chandrakant,Mukhopadyay, Debasmitha,Pushpavalli,Pal-Bhadra, Manika
, p. 697 - 703 (2013/06/05)
A series of novel imidazo[1,5-a]pyridine-PBD conjugates were synthesized and evaluated for their antitumor activity in breast cancer cell line (MCF-7). Interestingly, all the compounds showed enhanced DNA binding ability. These conjugates showed significa
