924656-53-1Relevant academic research and scientific papers
Total synthesis of brevenal
Zhang, Yuan,Rohanna, John,Zhou, Jie,Iyer, Karthik,Rainier, Jon D.
, p. 3208 - 3216 (2011/04/25)
This Article describes the total synthesis of the marine ladder toxin brevenal utilizing a convergent synthetic strategy. Critical to the success of this work was the use of olefinic-ester cyclization reactions and the utilization of glycal epoxides as precursors to C-C and C-H bonds.
Total synthesis, structure revision, and absolute configuration of (-)-brevenal
Fuwa, Haruhiko,Ebine, Makoto,Bourdelais, Andrea J.,Baden, Daniel G.,Sasaki, Makoto
, p. 16989 - 16999 (2007/10/03)
Total synthesis of structure 1 originally proposed for brevenal, a nontoxic polycyclic ether natural product isolated from the Florida red tide dinoflagellate, Karenia brevis, was accomplished. The key features of the synthesis involved (i) convergent ass
