924658-08-2Relevant academic research and scientific papers
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents
Zhou, Pengfei,Liang, Yuru,Zhang, Hao,Jiang, Hao,Feng, Kechang,Xu, Pan,Wang, Jie,Wang, Xiaoming,Ding, Kuiling,Luo, Cheng,Liu, Mingming,Wang, Yang
, p. 817 - 842 (2018/01/10)
A diverse of chiral β-lactam bridged analogues of combretastatin A-4 (CA-4), 3-substituted 1,4-diaryl-2-azetidinones, were asymmetrically synthesized and biologically evaluated, leading to identify a number of potent anti-proliferative compounds represent
Palladium-catalyzed α-regioselective allylic amination of Morita-Baylis-Hillman acetates with simple aromatic amines
Wang, Yan,Liu, Li,Wang, Dong,Chen, Yong-Jun
supporting information, p. 6908 - 6913 (2012/11/07)
An efficient allylic amination of Morita-Baylis-Hillman acetates with simple aromatic amines provided good yields with excellent α- regioselectivity (up to exclusive α-product) under the catalysis of Pd2(dba)3/ferrocene-type diphosph
Trifluoroacetic acid: a more effective and efficient reagent for the synthesis of 3-arylmethylene-3,4-dihydro-1H-quinolin-2-ones and 3-arylmethyl-2-amino-quinolines from Baylis-Hillman derivatives via Claisen rearrangement
Pathak, Richa,Madapa, Sudharshan,Batra, Sanjay
, p. 451 - 460 (2007/10/03)
Trifluoroacetic acid has been discovered to be a highly effective and efficient reagent for the tandem Claisen rearrangement and cyclization reaction to yield 3-arylmethylene-3,4-dihydro-1H-quinolin-2-ones from compounds obtained from the SN2 r
