92486-38-9

Basic information

• Product Name: 4-Ethyl-2-pyridinecarbonitrile
• Synonyms: 4-Ethyl-2-pyridinecarbonitrile;2-Cyano-4-ethylpyridine;2-Pyridinecarbonitrile, 4-ethyl-
• CAS NO: 92486-38-9
• Molecular Formula: C₈H₈N₂
• Molecular Weight: 132
• Product Categories: Aromatics;Heterocycles;Miscellaneous Reagents
• Mol File: 92486-38-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 123-124 °C(Press: 11 Torr)
• Appearance: /
• Density: 1.05±0.1 g/cm3(Predicted)
• Solubility: Chloroform, Dichloromethane, DMSO
• PKA: 0.48±0.10(Predicted)
• CAS DataBase Reference: 4-Ethyl-2-pyridinecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Ethyl-2-pyridinecarbonitrile(92486-38-9)
• EPA Substance Registry System: 4-Ethyl-2-pyridinecarbonitrile(92486-38-9)

Safety Data

• Hazardous Substances Data: 92486-38-9(Hazardous Substances Data)

Usage

Uses

4-Ethyl-2-pyridinecarbonitrile (cas# 92486-38-9) is a compound useful in organic synthesis.

Upstream product

• 536-75-4 4-Ethylpyridine 
• 7677-24-9 trimethylsilyl cyanide 
• 33252-32-3 4-ethylpyridin-2-amine 
• 54453-91-7 2-bromo-4-ethylpyridine 
• 14906-55-9 4-ethylpyridine-1-oxide 
• 100-70-9 2-Cyanopyridine 
• 64-17-5 ethanol 

Downstream Products

• 123811-85-8 (2S,4R)-4-Ethyl-piperidine-1,2-dicarboxylic acid 1-tert-butyl ester; compound with dicyclohexyl-amine 
• 123811-84-7 4-ethyl-BOC-DL-homoproline 
• 79415-24-0 (2R,4S)-4-Ethyl-piperidine-2-carboxylic acid 
• 79415-18-2 4-ethyl-2-pyridinecarboxylic acid hydrochloride 
• 59576-27-1 2-acetyl-4-ethylpyridine 

Relevant articles and documents

Ailanthoidine, a novel benzo[c]phenanthridine alkaloid with a cyanopyridine pendant, from a xanthoxylum species

The structure of ailanthoidine isolated from the bark of Xanthoxylum ailanthoides Sieb. et Zucc. has been deduced as 1 on the basis of its spectral data including 2-D NMR spectrosoopy and an X-ray analysis of 7B.

SUBSTITUTION OF ALKYL AND HYDROXYALKYL GROUP FOR RING HYDROGEN AND OF HYDROXYALKYL GROUP FOR CYANO GROUP IN GAMMA-IRRADIATION OF PYRIDINECARBONITRILES IN ALCOHOL

Gamma-irradiation of pyridinecarbonitriles in alcohol in the presence of sulfuric acid brings about the substitution of the alkyl group derived from alcohol for,the ring hydrogen, while that in the absence of sulfuric acid causes the substitution of hydroxyalkyl group for CN at the 2- and 4-positions.Hydroxyalkyl radicals and solvated electrons play important role in the substitution.