924883-56-7

Basic information

• Product Name: 2,3-DIMETHYL-6-(PYRIDIN-4-YL)IMIDAZO[2,1-B]THIAZOLE
• Synonyms: 2,3-DIMETHYL-6-(PYRIDIN-4-YL)IMIDAZO[2,1-B]THIAZOLE
• CAS NO: 924883-56-7
• Molecular Formula: C12H11N3S
• Molecular Weight: 229.3
• Mol File: 924883-56-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-DIMETHYL-6-(PYRIDIN-4-YL)IMIDAZO[2,1-B]THIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIMETHYL-6-(PYRIDIN-4-YL)IMIDAZO[2,1-B]THIAZOLE(924883-56-7)
• EPA Substance Registry System: 2,3-DIMETHYL-6-(PYRIDIN-4-YL)IMIDAZO[2,1-B]THIAZOLE(924883-56-7)

Safety Data

• Hazardous Substances Data: 924883-56-7(Hazardous Substances Data)

Upstream product

• 2289-75-0 4,5-dimethyl-thiazol-2-ylamine 
• 6221-13-2 4-(bromoacetyl)pyridine 

Downstream Products

• 924884-01-5 2,3-dimethyl-6-pyridin-4-yl-imidazo[2,1-b]thiazole-5-carbaldehyde 

Relevant articles and documents

Synthesis and antitumor activity of guanylhydrazones from 6-(2,4-dichloro-5-nitrophenyl)imidazo[2,1-b]thiazoles and 6-pyridylimidazo[2,1- b]thiazoles

The design and synthesis of antitumor imidazothiazole guanylhydrazones are reported. The compounds were submitted to NCI for testing. All but one were more active than methyl-GAG. A few compounds were selected for further studies in search of a possible mechanism of action. The results from these studies and a final search with the NCI COMPARE algorithm suggest that the guanylhydrazones described in this paper are acting through a novel mechanism of action.