92546-72-0

Usage

General Description

2-[3-(dimethylamino)phenyl]-2-propanol, also known as N,N-dimethyl-3-phenyl-3-(2-hydroxy-2-methylpropyl)propan-1-amine, is a chemical compound with the formula C13H21NO. It is a colorless liquid with a molecular weight of 207.31 g/mol. 2-[3-(dimethylamino)phenyl]-2-propanol is commonly used as a reagent in organic synthesis and is also known for its pharmaceutical properties, particularly as a precursor in the synthesis of certain drugs. It has been found to exhibit high potential as an analgesic. Additionally, it is known to have tranquilizing and antipsychotic effects, making it a useful compound in the pharmaceutical and medical industries.

InChI:InChI=1/C11H17NO/c1-11(2,13)9-6-5-7-10(8-9)12(3)4/h5-8,13H,1-4H3

Upstream product

• 18992-80-8 1-(3-dimethylaminophenyl)-1-ethanone 
• 16518-62-0 3-bromo-N,N-dimethylaniline 
• 67-64-1 acetone 
• 917-64-6 methyl magnesium iodide 
• 16518-64-2 3-(dimethylamino)benzoic acid methyl ester 

Downstream Products

• 35843-88-0 2-<3-(Dimethylamino)phenyl>propene 
• 1588767-67-2 N-(7-(dimethylamino)-9,9-dimethyl-10-(phenylethynyl)-anthracen-2(9H)-ylidene)-N-methylmethanaminium chloride 

Relevant academic research and scientific papers

Improved Xanthone Synthesis, Stepwise Chemical Redox Cycling

A base-catalyzed direct oxidation of rhodamine, carborhodamine, and siliconrhodamine pyronines to the corresponding xanthones is studied. This methodology utilizes addition of water to split pyronines into xanthone and reduced xanthene, the latter of whic

SiRA: A Silicon Rhodamine-Binding Aptamer for Live-Cell Super-Resolution RNA Imaging

Although genetically encoded light-up RNA aptamers have become promising tools for visualizing and tracking RNAs in living cells, aptamer/ligand pairs that emit in the far-red and near-infrared (NIR) regions are still rare. In this work, we developed a li

Near-infrared fluorescent 9-phenylethynylpyronin analogues for bioimaging

The syntheses and biological applications of two novel fluorescent 9-phenylethynylpyronin analogues containing either carbon or silicon at the position 10 are reported. Both fluorescent probes exhibited a relatively strong fluorescence in methanol and pho

Access to "friedel-Crafts-Restricted" tert -alkyl aromatics by activation/methylation of tertiary benzylic alcohols

Herein we describe a two-step protocol to prepare m-tert-alkylbenzenes. The appropriate tertiary benzylic alcohols are activated with SOCl2 or concentrated HCl and then treated with trimethylaluminum, affording the desired products in 68-97% yields (22 examples). This reaction sequence is successful in the presence of a variety of functional groups, including acid-sensitive and Lewis-basic groups. In addition to t-Bu groups, 1,1-dimethylpropyl and 1-ethyl-1-methylpropyl groups can also be installed using this method.