18992-80-8

Usage

Uses

Used in Organic Synthesis:
3'-DIMETHYLAMINOACETOPHENONE is used as a building block for the synthesis of various organic compounds. Its unique structure allows for the creation of a wide range of chemical entities, making it a valuable component in the development of new organic materials.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3'-DIMETHYLAMINOACETOPHENONE is utilized as a precursor in the production of certain pharmaceutical drugs. Its reactivity and structural features enable the synthesis of drug candidates with potential therapeutic applications.
Used in Biological Activity Studies:
3'-DIMETHYLAMINOACETOPHENONE is studied for its potential antibacterial and antifungal properties. Its ability to interact with biological systems makes it a candidate for the development of new antimicrobial agents to combat resistant strains of bacteria and fungi.
Overall, 3'-DIMETHYLAMINOACETOPHENONE's multifaceted applications in organic synthesis, pharmaceutical research, and biological activity studies underscore its importance in advancing scientific knowledge and developing innovative solutions in the chemical and medical fields.

InChI:InChI=1/C30H58O2/c1-3-5-7-9-11-13-14-15-16-17-18-19-21-23-25-27-29-32-30(31)28-26-24-22-20-12-10-8-6-4-2/h15-16H,3-14,17-29H2,1-2H3/b16-15-

Upstream product

• 917-64-6 methyl magnesium iodide 
• 33225-17-1 3-(dimethylamino)benzamide 
• 38803-30-4 3-(dimethylamino)benzonitrile 
• 99-03-6 1-(3-aminophenyl)ethanone 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 512-56-1 trimethyl phosphite 
• 13411-48-8 1-(trimethylsilyl)ethanone 
• 16518-62-0 3-bromo-N,N-dimethylaniline 
• 5339-01-5 1-(3-(dimethylamino)phenyl)ethan-1-ol 
• 67-56-1 methanol 
• 121-89-1 3-Nitroacetophenone 

Downstream Products

• 105910-83-6 (3-dimethylamino-phenyl)-thioacetic acid dimethylamide 
• 1429243-12-8 3-amino-6-(3-(dimethylamino)phenyl)thieno[2,3-b]pyridine-2-carboxamide 
• 1429243-20-8 C₁₄H₁₃N₃S 
• 791818-27-4 C₁₃H₁₈N₂O 
• 1360454-71-2 (R)-1-(3-(dimethylamino)phenyl)ethan-1-ol 
• 1207717-71-2 (S)-1-(3-dimethylaminophenyl)ethan-1-ol 
• 5339-01-5 1-(3-(dimethylamino)phenyl)ethan-1-ol 

Relevant academic research and scientific papers

Commercial Pd/C-Catalyzed N-Methylation of Nitroarenes and Amines Using Methanol as Both C1 and H2 Source

Herein, we report commercially available carbon-supported-palladium (Pd/C)-catalyzed N-methylation of nitroarenes and amines using MeOH as both a C1 and a H2 source. This transformation proceeds with high atom-economy and in an environmentally friendly way via borrowing hydrogen mechanism. A total of >30 structurally diverse N-methylamines, including bioactive compounds, were selectively synthesized with isolated yields of up to 95%. Furthermore, selective N-methylation and deuteration of nimesulide, a nonsteroidal anti-inflammatory drug, were realized through the late-stage functionalization.

METHOD OF PRODUCING ORGANIC COMPOUND

A method of producing an organic compound, which contains a step of performing a deodorization step using a flow reaction in a flow passage to remove, from a reaction liquid, a malodorous material generated or remaining in a reaction step, wherein the organic compound is an industrially useful compound.

Palladium-catalyzed acetylation of arenes

A simple method for the preparation of aryl methyl ketones is reported. The transformation involves the Pd-catalyzed coupling of an acyl anion equivalent, acetyltrimethylsilane, with aryl bromides to afford the corresponding acetylated arenes in synthetically useful yields. The methodology is tolerant of heterocycles and provides a new method for arene functionalization.