925463-68-9

Upstream product

• 129464-01-3 2-(benzyloxy)-4-fluoro-1-nitrobenzene 
• 446-36-6 5-fluoro-2-nitrophenol 
• 925463-62-3 N-(2-benzyloxy-8-methyl-4-triisopropylsilanyloxy-5,8-dihydro-naphthalen-1-yl)-4-methyl-benzenesulfonamide 
• 925463-61-2 N-(2-benzyloxy-4-hydroxy-8-methyl-5,8-dihydro-naphthalen-1-yl)-4-methyl-benzenesulfonamide 
• 925463-44-1 N-(2-benzyloxy-4-hydroxy-phenyl)-4-methyl-benzenesulfonamide 
• 221615-94-7 3-(benzyloxy)-4-nitrophenol 
• 925463-43-0 4-amino-3-benzyloxy-phenol 
• 925463-67-8 [4-benzyloxy-8-methoxymethoxy-1-methyl-3-(toluene-4-sulfonyl)-8,9-dihydro-3H,7H-pyrrolo[3,2-f]quinolin-6-yl]-phenyl-methanone 
• 925463-66-7 trifluoro-methanesulfonic acid 4-(3-benzoylamino-2-methoxymethoxy-propyl)-7-benzyloxy-3-methyl-1-(toluene-4-sulfonyl)-1H-indol-5-yl ester 
• 925463-64-5 3-[7-benzyloxy-3-methyl-1-(toluene-4-sulfonyl)-5-triisopropylsilanyloxy-1H-indol-4-yl]-2-methoxymethoxy-propionitrile 
• 925463-74-7 N-{3-[7-benzyloxy-5-hydroxy-3-methyl-1-(toluene-4-sulfonyl)-1H-indol-4-yl]-2-methoxymethoxy-propyl}-benzamide 
• 925463-73-6 3-[7-benzyloxy-3-methyl-1-(toluene-4-sulfonyl)-5-triisopropylsilanyloxy-1H-indol-4-yl]-2-hydroxy-propionitrile 
• 925463-63-4 [7-benzyloxy-3-methyl-1-(toluene-4-sulfonyl)-5-triisopropylsilanyloxy-1H-indol-4-yl]-acetaldehyde 
• 925463-65-6 N-{3-[7-benzyloxy-3-methyl-1-(toluene-4-sulfonyl)-5-triisopropylsilanyloxy-1H-indol-4-yl]-2-methoxymethoxy-propyl}-benzamide 

Relevant academic research and scientific papers

Aryl amidation routes to dihydropyrrolo[3,2-e]indoles and pyrrolo[3,2-f]tetrahydroquinolines: Total synthesis of the (±)-CC-1065 CPI subunit

CC-1065 and the related duocarmycins are members of a structurally unique family of naturally occurring molecules and remain some of the most rigorously studied antitumor compounds to date. Herein we describe a total synthesis of the (±)-CC-1065 CPI subun